Pathways

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BRENDA KEGG MetaCyc

pentose phosphate pathway (BRENDA)
:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+
: pentose phosphate pathway
: Pentose phosphate pathway,
Glutathione metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: heterolactic fermentation,
pentose phosphate pathway (oxidative branch) I
: BR29307show the reaction diagram
: R01528show the reaction diagram
: 6PGLUCONDEHYDROG-RXNshow the reaction diagram, RXN-9952show the reaction diagram
: 108
-
-
-
: NAD+ (see R10221)
natural substrates
phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+
: pentose phosphate pathway
: Pentose phosphate pathway,
Glutathione metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: heterolactic fermentation,
pentose phosphate pathway (oxidative branch) I
: BR29307show the reaction diagram
: R01528show the reaction diagram
: 6PGLUCONDEHYDROG-RXNshow the reaction diagram, RXN-9952show the reaction diagram
: 108
-
-
-
: NAD+ (see R10221)
natural substrates
6-phosphogluconolactonase
6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate
: pentose phosphate pathway
: Pentose phosphate pathway,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: Entner-Doudoroff pathway I,
superpathway of glycolysis and the Entner-Doudoroff pathway,
heterolactic fermentation,
formaldehyde oxidation I,
pentose phosphate pathway (oxidative branch) I
: BR10654show the reaction diagram
: R02035show the reaction diagram
: 6PGLUCONOLACT-RXNshow the reaction diagram
: 109
-
-
-
-
natural substrates
glucose-6-phosphate dehydrogenase [NAD(P)+]
D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH + H+
: pentose phosphate pathway
: Entner-Doudoroff pathway I,
superpathway of glycolysis and the Entner-Doudoroff pathway,
formaldehyde oxidation I,
heterolactic fermentation,
pentose phosphate pathway (oxidative branch) I,
cytosolic NADPH production (yeast)
: BR29312show the reaction diagram
: R00835show the reaction diagram
: GLU6PDEHYDROG-RXNshow the reaction diagram, RXN-14819show the reaction diagram
: 1176, 6509
-
-
-
-
natural substrates
glucose 1-dehydrogenase [NAD(P)+]
D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH + H+
: pentose phosphate pathway
: Entner-Doudoroff pathway I,
superpathway of glycolysis and the Entner-Doudoroff pathway,
formaldehyde oxidation I,
heterolactic fermentation,
pentose phosphate pathway (oxidative branch) I,
cytosolic NADPH production (yeast)
: BR29312show the reaction diagram
: R00835show the reaction diagram
: GLU6PDEHYDROG-RXNshow the reaction diagram, RXN-14819show the reaction diagram
: 1176, 6509
-
-
-
-
natural substrates
glucose-6-phosphate dehydrogenase (NADP+)
D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH + H+
: pentose phosphate pathway
: Entner-Doudoroff pathway I,
superpathway of glycolysis and the Entner-Doudoroff pathway,
formaldehyde oxidation I,
heterolactic fermentation,
pentose phosphate pathway (oxidative branch) I,
cytosolic NADPH production (yeast)
: BR29312show the reaction diagram
: R00835show the reaction diagram
: GLU6PDEHYDROG-RXNshow the reaction diagram, RXN-14819show the reaction diagram
: 1176, 6509
-
-
-
-
natural substrates
transketolase
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate
: pentose phosphate pathway,
photosynthesis
: Pentose phosphate pathway,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of amino acids
: pentose phosphate pathway (non-oxidative branch) II,
Bifidobacterium shunt,
Calvin-Benson-Bassham cycle,
Rubisco shunt,
pentose phosphate pathway (non-oxidative branch) I,
formaldehyde assimilation III (dihydroxyacetone cycle),
formaldehyde assimilation II (assimilatory RuMP Cycle),
pentose phosphate pathway (partial)
: BR43957show the reaction diagram, BS320211show the reaction diagram
: R01641show the reaction diagram
: 1TRANSKETO-RXNshow the reaction diagram
-
-
-
: TPP-dependent enzyme (see R06863+R06861)
natural substrates
formaldehyde transketolase
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate
: pentose phosphate pathway,
photosynthesis
: Pentose phosphate pathway,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of amino acids
: pentose phosphate pathway (non-oxidative branch) II,
Bifidobacterium shunt,
Calvin-Benson-Bassham cycle,
Rubisco shunt,
pentose phosphate pathway (non-oxidative branch) I,
formaldehyde assimilation III (dihydroxyacetone cycle),
formaldehyde assimilation II (assimilatory RuMP Cycle),
pentose phosphate pathway (partial)
: BR43957show the reaction diagram, BS320211show the reaction diagram
: R01641show the reaction diagram
: 1TRANSKETO-RXNshow the reaction diagram
-
-
-
: TPP-dependent enzyme (see R06863+R06861)
natural substrates
ribulose-phosphate 3-epimerase
D-ribulose 5-phosphate = D-xylulose 5-phosphate
: pentose phosphate pathway,
photosynthesis
: Pentose phosphate pathway,
Pentose and glucuronate interconversions,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of amino acids
: pentose phosphate pathway (non-oxidative branch) II,
Bifidobacterium shunt,
heterolactic fermentation,
Calvin-Benson-Bassham cycle,
Rubisco shunt,
pentose phosphate pathway (non-oxidative branch) I,
formaldehyde assimilation III (dihydroxyacetone cycle),
formaldehyde assimilation II (assimilatory RuMP Cycle),
pentose phosphate pathway (partial)
: BR184show the reaction diagram
: R01529show the reaction diagram
: RIBULP3EPIM-RXNshow the reaction diagram
: 62
-
-
-
-
natural substrates
D-erythrulose 4-phosphate isomerase
D-ribulose 5-phosphate = D-xylulose 5-phosphate
: pentose phosphate pathway,
photosynthesis
: Pentose phosphate pathway,
Pentose and glucuronate interconversions,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of amino acids
: pentose phosphate pathway (non-oxidative branch) II,
Bifidobacterium shunt,
heterolactic fermentation,
Calvin-Benson-Bassham cycle,
Rubisco shunt,
pentose phosphate pathway (non-oxidative branch) I,
formaldehyde assimilation III (dihydroxyacetone cycle),
formaldehyde assimilation II (assimilatory RuMP Cycle),
pentose phosphate pathway (partial)
: BR184show the reaction diagram
: R01529show the reaction diagram
: RIBULP3EPIM-RXNshow the reaction diagram
: 62
-
-
-
-
natural substrates
ribose-5-phosphate isomerase
D-Ribose 5-phosphate = D-ribulose 5-phosphate
: pentose phosphate pathway,
photosynthesis
: Pentose phosphate pathway,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of amino acids
: pentose phosphate pathway (non-oxidative branch) II,
Bifidobacterium shunt,
Calvin-Benson-Bassham cycle,
Rubisco shunt,
pentose phosphate pathway (non-oxidative branch) I,
formaldehyde assimilation III (dihydroxyacetone cycle),
formaldehyde assimilation II (assimilatory RuMP Cycle)
: BR237show the reaction diagram
: R01056show the reaction diagram
: RIB5PISOM-RXNshow the reaction diagram
-
-
-
-
natural substrates
transketolase
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate
: pentose phosphate pathway
: Pentose phosphate pathway,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of amino acids
: Bifidobacterium shunt,
formaldehyde assimilation III (dihydroxyacetone cycle),
Rubisco shunt,
pentose phosphate pathway (non-oxidative branch) I,
formaldehyde assimilation II (assimilatory RuMP Cycle)
: BR43958show the reaction diagram, BS409136show the reaction diagram
: R01827show the reaction diagram, R08575show the reaction diagram
: TRANSALDOL-RXNshow the reaction diagram
: 8744
-
-
-
-
natural substrates
transaldolase
sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate
: pentose phosphate pathway
: Pentose phosphate pathway,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of amino acids
: Bifidobacterium shunt,
formaldehyde assimilation III (dihydroxyacetone cycle),
Rubisco shunt,
pentose phosphate pathway (non-oxidative branch) I,
formaldehyde assimilation II (assimilatory RuMP Cycle)
: BR43958show the reaction diagram, BS409136show the reaction diagram
: R01827show the reaction diagram, R08575show the reaction diagram
: TRANSALDOL-RXNshow the reaction diagram
: 8744
-
-
-
-
natural substrates
transketolase
D-xylulose 5-phosphate + D-erythrose 4-phosphate = D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate
: pentose phosphate pathway,
photosynthesis
: Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
Pentose phosphate pathway,
Biosynthesis of secondary metabolites,
Biosynthesis of amino acids
: pentose phosphate pathway (non-oxidative branch) II,
superpathway of glucose and xylose degradation,
Calvin-Benson-Bassham cycle,
Rubisco shunt,
pentose phosphate pathway (non-oxidative branch) I,
formaldehyde assimilation III (dihydroxyacetone cycle),
formaldehyde assimilation II (assimilatory RuMP Cycle),
pentose phosphate pathway (partial)
: BS320170show the reaction diagram, BS320221show the reaction diagram, BS434641show the reaction diagram
: R01067show the reaction diagram, R01830show the reaction diagram
: 2TRANSKETO-RXNshow the reaction diagram
: 1337
-
-
-
-
natural substrates
formaldehyde transketolase
D-xylulose 5-phosphate + D-erythrose 4-phosphate = D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate
: pentose phosphate pathway,
photosynthesis
: Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
Pentose phosphate pathway,
Biosynthesis of secondary metabolites,
Biosynthesis of amino acids
: pentose phosphate pathway (non-oxidative branch) II,
superpathway of glucose and xylose degradation,
Calvin-Benson-Bassham cycle,
Rubisco shunt,
pentose phosphate pathway (non-oxidative branch) I,
formaldehyde assimilation III (dihydroxyacetone cycle),
formaldehyde assimilation II (assimilatory RuMP Cycle),
pentose phosphate pathway (partial)
: BS320170show the reaction diagram, BS320221show the reaction diagram, BS434641show the reaction diagram
: R01067show the reaction diagram, R01830show the reaction diagram
: 2TRANSKETO-RXNshow the reaction diagram
: 1337
-
-
-
-
natural substrates
glucose-6-phosphate 1-epimerase
alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate
: pentose phosphate pathway
: Glycolysis / Gluconeogenesis,
Pentose phosphate pathway,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments
: BR190show the reaction diagram
: R02739show the reaction diagram
: GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXNshow the reaction diagram
: 13
-
-
-
-
natural substrates
Aldose 1-epimerase
alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate
: pentose phosphate pathway
: Glycolysis / Gluconeogenesis,
Pentose phosphate pathway,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments
: BR190show the reaction diagram
: R02739show the reaction diagram
: GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXNshow the reaction diagram
: 13
-
-
-
-
natural substrates
glucose-6-phosphate isomerase
alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate
: pentose phosphate pathway
: Glycolysis / Gluconeogenesis,
Pentose phosphate pathway,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments
: BR190show the reaction diagram
: R02739show the reaction diagram
: GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXNshow the reaction diagram
: 13
-
-
-
-
natural substrates
fructose-bisphosphatase
sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate
: photosynthesis,
pentose phosphate pathway
: Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: Calvin-Benson-Bassham cycle
: BR15940show the reaction diagram
: R01845show the reaction diagram
: SEDOHEPTULOSE-BISPHOSPHATASE-RXNshow the reaction diagram
: 1923
-
-
-
-
natural substrates
sedoheptulose-bisphosphatase
sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate
: photosynthesis,
pentose phosphate pathway
: Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: Calvin-Benson-Bassham cycle
: BR15940show the reaction diagram
: R01845show the reaction diagram
: SEDOHEPTULOSE-BISPHOSPHATASE-RXNshow the reaction diagram
: 1923
-
-
-
-
natural substrates
3-hexulose-6-phosphate synthase
D-arabino-hex-3-ulose 6-phosphate = D-ribulose 5-phosphate + formaldehyde
: ribulose monophosphate pathway,
pentose phosphate pathway
: Pentose phosphate pathway,
Methane metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of amino acids
: pentose phosphate pathway (oxidative branch) II,
formaldehyde oxidation I,
formaldehyde assimilation II (assimilatory RuMP Cycle)
: BR48972show the reaction diagram
: R05338show the reaction diagram
: R10-RXNshow the reaction diagram
: 561
-
-
-
-
natural substrates
6-phospho-3-hexuloisomerase
D-arabino-hex-3-ulose 6-phosphate = D-fructose 6-phosphate
: ribulose monophosphate pathway,
pentose phosphate pathway
: Methane metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
Pentose phosphate pathway,
Biosynthesis of amino acids
: pentose phosphate pathway (oxidative branch) II,
formaldehyde oxidation I,
formaldehyde assimilation II (assimilatory RuMP Cycle)
: BR48975show the reaction diagram
: R05339show the reaction diagram, R09780show the reaction diagram
: R12-RXNshow the reaction diagram
: 560
-
-
-
-
natural substrates
glucose-6-phosphate dehydrogenase [NAD(P)+]
D-glucose 6-phosphate + NAD+ = 6-phospho-D-glucono-1,5-lactone + NADH + H+
: pentose phosphate pathway
: BR50596_WOPThis reaction also exists with phosphate.show the reaction diagram
: R10520show the reaction diagram
: RXN-14819_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-16652show the reaction diagram
: 7793, 7796
-
-
-
-
natural substrates
glucose-6-phosphate dehydrogenase (NAD+)
D-glucose 6-phosphate + NAD+ = 6-phospho-D-glucono-1,5-lactone + NADH + H+
: pentose phosphate pathway
: BR50596_WOPThis reaction also exists with phosphate.show the reaction diagram
: R10520show the reaction diagram
: RXN-14819_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-16652show the reaction diagram
: 7793, 7796
-
-
-
-
natural substrates
glucose 1-dehydrogenase [NAD(P)+]
D-glucose 6-phosphate + NAD+ = 6-phospho-D-glucono-1,5-lactone + NADH + H+
: pentose phosphate pathway
: BR50596_WOPThis reaction also exists with phosphate.show the reaction diagram
: R10520show the reaction diagram
: RXN-14819_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-16652show the reaction diagram
: 7793, 7796
-
-
-
-
natural substrates
glucose-6-phosphate dehydrogenase (NADP+)
D-glucose 6-phosphate + NAD+ = 6-phospho-D-glucono-1,5-lactone + NADH + H+
: pentose phosphate pathway
: BR50596_WOPThis reaction also exists with phosphate.show the reaction diagram
: R10520show the reaction diagram
: RXN-14819_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-16652show the reaction diagram
: 7793, 7796
-
-
-
-
natural substrates
phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating)
6-phospho-D-gluconate + NAD+ = D-ribulose 5-phosphate + CO2 + NADH + H+
: pentose phosphate pathway
: Pentose phosphate pathway,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: heterolactic fermentation,
formaldehyde oxidation I
: BR50378show the reaction diagram
: R10221show the reaction diagram
: 6PGLUCONDEHYDROG-RXN_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-3341show the reaction diagram
: 9789
-
-
-
: NADP+ (see R01528)
natural substrates
phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
6-phospho-D-gluconate + NAD+ = D-ribulose 5-phosphate + CO2 + NADH + H+
: pentose phosphate pathway
: Pentose phosphate pathway,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: heterolactic fermentation,
formaldehyde oxidation I
: BR50378show the reaction diagram
: R10221show the reaction diagram
: 6PGLUCONDEHYDROG-RXN_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-3341show the reaction diagram
: 9789
-
-
-
: NADP+ (see R01528)
natural substrates
phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
6-phospho-D-gluconate + NAD+ = D-ribulose 5-phosphate + CO2 + NADH + H+
: pentose phosphate pathway
: Pentose phosphate pathway,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: heterolactic fermentation,
formaldehyde oxidation I
: BR50378show the reaction diagram
: R10221show the reaction diagram
: 6PGLUCONDEHYDROG-RXN_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-3341show the reaction diagram
: 9789
-
-
-
: NADP+ (see R01528)
natural substrates