Print
pantoate-beta-alanine ligase (AMP-forming)
Pathways
pantothenate biosynthesis (BRENDA)
:= BRENDA, 
:= KEGG, 
:= MetaCyc, 
:= SABIO-RK
:= amino acid sequences 
:= show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate
; "show the reaction diagram")
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natural substrates
3-methyl-2-oxobutanoate hydroxymethyltransferase
5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = tetrahydrofolate + 2-dehydropantoate
; "show the reaction diagram")
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: multi-step reactionnatural substrates, multi-step reaction
2-dehydropantoate 2-reductase
(R)-pantoate + NADP+ = 2-dehydropantoate + NADPH + H+
; "show the reaction diagram")
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natural substrates
ketol-acid reductoisomerase (NADP+)
(R)-pantoate + NADP+ = 2-dehydropantoate + NADPH + H+
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natural substrates
pantoate kinase
ATP + (R)-pantoate = ADP + (R)-4-phosphopantoate
; "show the reaction diagram")
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natural substrates
4-phosphopantoate-beta-alanine ligase
ATP + (R)-4-phosphopantoate + beta-alanine = AMP + diphosphate + (R)-4'-phosphopantothenate
; "show the reaction diagram")
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natural substrates
pantoate-beta-alanine ligase (ADP-forming)
ATP + (R)-pantoate + beta-alanine = ADP + phosphate + (R)-pantothenate
; "show the reaction diagram")
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natural substrates