Print
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
Pathways
palmitate biosynthesis (BRENDA)
:= BRENDA, 
:= KEGG, 
:= MetaCyc, 
:= SABIO-RK
:= amino acid sequences 
:= show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
(3R)-3-hydroxyhexanoyl-[acyl-carrier protein] = 2-hexenoyl-[acyl-carrier protein] + H2O
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butyryl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = beta-ketohexanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
; "show the reaction diagram")
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase II
butyryl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = beta-ketohexanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase I
butyryl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = beta-ketohexanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
fatty-acid synthase system
butyryl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = beta-ketohexanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
fatty-acyl-CoA synthase system
butyryl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = beta-ketohexanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
enoyl-[acyl-carrier-protein] reductase (NADH)
crotonyl-[acyl-carrier protein] + NADH = butyryl-[acyl-carrier protein] + NAD+
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protein
enoyl-[acyl-carrier-protein] reductase (NADH)
2-octenoyl-[acyl-carrier protein] + NADH = octanoyl-[acyl-carrier protein] + NAD+
; "show the reaction diagram")
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natural substrates
2-octenoyl-[acyl-carrier protein] + NADH = octanoyl-[acyl-carrier protein] + NAD+
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase I
hexanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxooctanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
; "show the reaction diagram")
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natural substrates
fatty-acid synthase system
hexanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxooctanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
fatty-acyl-CoA synthase system
hexanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxooctanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
hexanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxooctanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase II
hexanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxooctanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
(3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = (2E)-2-octenoyl-[acyl-carrier protein] + H2O
; "show the reaction diagram")
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natural substrates
(3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = (2E)-2-octenoyl-[acyl-carrier protein] + H2O
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natural substrates
(3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = (2E)-2-octenoyl-[acyl-carrier protein] + H2O
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natural substrates
fatty-acid synthase system
(3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = (2E)-2-octenoyl-[acyl-carrier protein] + H2O
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natural substrates
fatty-acyl-CoA synthase system
(3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = (2E)-2-octenoyl-[acyl-carrier protein] + H2O
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natural substrates
enoyl-[acyl-carrier-protein] reductase (NADH)
2-hexenoyl-[acyl-carrier protein] + NADH = hexanoyl-[acyl-carrier protein] + NAD+
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protein
acetoacetyl-[acyl-carrier protein] + NADPH = D-beta-hydroxybutyryl-[acyl-carrier protein] + NADP+
; "show the reaction diagram")
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natural substrates
3-oxoacyl-[acyl-carrier-protein] reductase
acetoacetyl-[acyl-carrier protein] + NADPH = D-beta-hydroxybutyryl-[acyl-carrier protein] + NADP+
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natural substrates
acetoacetyl-[acyl-carrier protein] + NADPH = D-beta-hydroxybutyryl-[acyl-carrier protein] + NADP+
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natural substrates
fatty-acid synthase system
acetoacetyl-[acyl-carrier protein] + NADPH = D-beta-hydroxybutyryl-[acyl-carrier protein] + NADP+
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natural substrates
fatty-acyl-CoA synthase system
acetoacetyl-[acyl-carrier protein] + NADPH = D-beta-hydroxybutyryl-[acyl-carrier protein] + NADP+
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natural substrates
octanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxodecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
; "show the reaction diagram")
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase II
octanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxodecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase I
octanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxodecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
fatty-acid synthase system
octanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxodecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
fatty-acyl-CoA synthase system
octanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxodecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
tetradecanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxohexadecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
; "show the reaction diagram")
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase II
tetradecanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxohexadecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase I
tetradecanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxohexadecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
fatty-acid synthase system
tetradecanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxohexadecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
fatty-acyl-CoA synthase system
tetradecanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxohexadecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
trans-2-enoyl-CoA reductase (NADPH)
2-dodecenoyl-[acyl-carrier protein] + NADH = dodecanoyl-[acyl-carrier protein] + NAD+
; "show the reaction diagram")
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natural substrates
enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2-dodecenoyl-[acyl-carrier protein] + NADH = dodecanoyl-[acyl-carrier protein] + NAD+
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natural substrates
enoyl-[acyl-carrier-protein] reductase (NADH)
2-dodecenoyl-[acyl-carrier protein] + NADH = dodecanoyl-[acyl-carrier protein] + NAD+
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natural substrates
2-dodecenoyl-[acyl-carrier protein] + NADH = dodecanoyl-[acyl-carrier protein] + NAD+
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase I
dodecanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxotetradecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
; "show the reaction diagram")
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natural substrates
fatty-acid synthase system
dodecanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxotetradecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
fatty-acyl-CoA synthase system
dodecanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxotetradecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
dodecanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxotetradecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase II
dodecanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxotetradecanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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natural substrates
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
(3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl-carrier protein] + H2O
; "show the reaction diagram")
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natural substrates, generic, protein
(3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl-carrier protein] + H2O
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natural substrates, generic, protein
fatty-acid synthase system
(3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl-carrier protein] + H2O
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natural substrates, generic, protein
fatty-acyl-CoA synthase system
(3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl-carrier protein] + H2O
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natural substrates, generic, protein
(3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl-carrier protein] + H2O
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natural substrates, generic, protein
enoyl-[acyl-carrier-protein] reductase (NADH)
trans-2-decenoyl-[acyl-carrier protein] + NADH = decanoyl-[acyl-carrier protein] + NAD+
; "show the reaction diagram")
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natural substrates
trans-2-decenoyl-[acyl-carrier protein] + NADH = decanoyl-[acyl-carrier protein] + NAD+
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natural substrates
a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = a 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
; "show the reaction diagram")
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: general reaction (see R04533, R04534, R04536, R04543, R04566, R04953, R04964 and R07763)natural substrates, generic, protein
3-oxoacyl-[acyl-carrier-protein] reductase
a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = a 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
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: general reaction (see R04533, R04534, R04536, R04543, R04566, R04953, R04964 and R07763)natural substrates, generic, protein
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
(3R)-3-hydroxydodecanoyl-[acyl-carrier protein] = 2-dodecenoyl-[acyl-carrier protein] + H2O
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natural substrates, protein
oleoyl-[acyl-carrier-protein] hydrolase
hexadecanoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + hexadecanoate
; "show the reaction diagram")
; "show the reaction diagram")
; "show the reaction diagram")
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: the last step (thioester-hydrolysing) of fatty-acid synthase (ec 2.3.1.85, see R05188, map00061); general reactionnatural substrates, generic, protein
dodecanoyl-[acyl-carrier-protein] hydrolase
hexadecanoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + hexadecanoate
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: the last step (thioester-hydrolysing) of fatty-acid synthase (ec 2.3.1.85, see R05188, map00061); general reactionnatural substrates, generic, protein
fatty-acid synthase system
hexadecanoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + hexadecanoate
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: the last step (thioester-hydrolysing) of fatty-acid synthase (ec 2.3.1.85, see R05188, map00061); general reactionnatural substrates, generic, protein
oleoyl-[acyl-carrier-protein] hydrolase
a dodecanoyl-[acyl-carrier protein] + H2O = an [acyl-carrier protein] + dodecanoate
; "show the reaction diagram")
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natural substrates
dodecanoyl-[acyl-carrier-protein] hydrolase
a dodecanoyl-[acyl-carrier protein] + H2O = an [acyl-carrier protein] + dodecanoate
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natural substrates