Pathways

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BRENDA KEGG MetaCyc

methylaspartate cycle (BRENDA)
:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
malyl-CoA lyase
(2R,3S)-2-methylmalyl-CoA = propanoyl-CoA + glyoxylate
: ethylmalonyl-CoA pathway,
methylaspartate cycle
: Glyoxylate and dicarboxylate metabolism,
C5-Branched dibasic acid metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: methylaspartate cycle,
glyoxylate assimilation,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
ethylmalonyl-CoA pathway
: BR50832show the reaction diagram
: R00934show the reaction diagram
: RXN-8961show the reaction diagram
: 1252
-
-
-
-
natural substrates
isocitrate dehydrogenase (NAD+)
isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+
: citric acid cycle,
methylaspartate cycle
: Glutathione metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: BR29305show the reaction diagram
: R00267show the reaction diagram
: 269
-
-
-
: two-step reaction (see R01899+R00268)
natural substrates
isocitrate dehydrogenase (NADP+)
isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+
: citric acid cycle,
methylaspartate cycle
: Glutathione metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: BR29305show the reaction diagram
: R00267show the reaction diagram
: 269
-
-
-
: two-step reaction (see R01899+R00268)
natural substrates
homoisocitrate dehydrogenase
isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+
: citric acid cycle,
methylaspartate cycle
: Glutathione metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: BR29305show the reaction diagram
: R00267show the reaction diagram
: 269
-
-
-
: two-step reaction (see R01899+R00268)
natural substrates
2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
citrate = cis-aconitate + H2O
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Glyoxylate and dicarboxylate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
2-Oxocarboxylic acid metabolism
: reductive TCA cycle I,
nitrogen remobilization from senescing leaves,
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle VII (acetate-producers),
partial TCA cycle (obligate autotrophs),
TCA cycle III (animals),
methylaspartate cycle,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
reductive TCA cycle II,
ethene biosynthesis V (engineered),
glyoxylate cycle,
mixed acid fermentation,
TCA cycle VI (Helicobacter)
: BR419show the reaction diagram
: R01325show the reaction diagram
: ACONITATEDEHYDR-RXNshow the reaction diagram
: 268
-
-
-
-
natural substrates
aconitate hydratase
citrate = cis-aconitate + H2O
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Glyoxylate and dicarboxylate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
2-Oxocarboxylic acid metabolism
: reductive TCA cycle I,
nitrogen remobilization from senescing leaves,
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle VII (acetate-producers),
partial TCA cycle (obligate autotrophs),
TCA cycle III (animals),
methylaspartate cycle,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
reductive TCA cycle II,
ethene biosynthesis V (engineered),
glyoxylate cycle,
mixed acid fermentation,
TCA cycle VI (Helicobacter)
: BR419show the reaction diagram
: R01325show the reaction diagram
: ACONITATEDEHYDR-RXNshow the reaction diagram
: 268
-
-
-
-
natural substrates
citrate = cis-aconitate + H2O
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Glyoxylate and dicarboxylate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
2-Oxocarboxylic acid metabolism
: reductive TCA cycle I,
nitrogen remobilization from senescing leaves,
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle VII (acetate-producers),
partial TCA cycle (obligate autotrophs),
TCA cycle III (animals),
methylaspartate cycle,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
reductive TCA cycle II,
ethene biosynthesis V (engineered),
glyoxylate cycle,
mixed acid fermentation,
TCA cycle VI (Helicobacter)
: BR419show the reaction diagram
: R01325show the reaction diagram
: ACONITATEDEHYDR-RXNshow the reaction diagram
: 268
-
-
-
-
natural substrates
2-methylfumaryl-CoA hydratase
(2R,3S)-2-methylmalyl-CoA = 2-methylfumaryl-CoA + H2O
: ethylmalonyl-CoA pathway,
methylaspartate cycle
: Glyoxylate and dicarboxylate metabolism,
C5-Branched dibasic acid metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: methylaspartate cycle,
glyoxylate assimilation,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
ethylmalonyl-CoA pathway
: BR51001show the reaction diagram
: R05076show the reaction diagram
: RXN-8960show the reaction diagram
-
-
-
-
natural substrates
3-methylfumaryl-CoA hydratase
(2R,3S)-2-methylmalyl-CoA = 2-methylfumaryl-CoA + H2O
: ethylmalonyl-CoA pathway,
methylaspartate cycle
: Glyoxylate and dicarboxylate metabolism,
C5-Branched dibasic acid metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: methylaspartate cycle,
glyoxylate assimilation,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
ethylmalonyl-CoA pathway
: BR51001show the reaction diagram
: R05076show the reaction diagram
: RXN-8960show the reaction diagram
-
-
-
-
natural substrates
methylaspartate mutase
L-threo-3-methylaspartate = L-glutamate
: glutamate and glutamine metabolism,
methylaspartate cycle
: Glyoxylate and dicarboxylate metabolism,
C5-Branched dibasic acid metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: methylaspartate cycle,
L-glutamate degradation VI (to pyruvate),
L-isoleucine biosynthesis III
: BR33show the reaction diagram
: R00262show the reaction diagram
: METHYLASPARTATE-MUTASE-RXNshow the reaction diagram
: 767
-
-
-
-
natural substrates
fumarate hydratase
(S)-malate = fumarate + H2O
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle VII (acetate-producers),
partial TCA cycle (obligate autotrophs),
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
methylaspartate cycle,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, mitochondrial),
reductive TCA cycle II,
incomplete reductive TCA cycle,
mixed acid fermentation,
TCA cycle VI (Helicobacter)
: BR3389show the reaction diagram
: R01082show the reaction diagram
: FUMHYDR-RXNshow the reaction diagram
: 256
-
-
-
-
natural substrates
(S)-2-methylmalate dehydratase
(S)-malate = fumarate + H2O
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle VII (acetate-producers),
partial TCA cycle (obligate autotrophs),
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
methylaspartate cycle,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, mitochondrial),
reductive TCA cycle II,
incomplete reductive TCA cycle,
mixed acid fermentation,
TCA cycle VI (Helicobacter)
: BR3389show the reaction diagram
: R01082show the reaction diagram
: FUMHYDR-RXNshow the reaction diagram
: 256
-
-
-
-
natural substrates
methylaspartate ammonia-lyase
L-threo-3-methylaspartate = mesaconate + NH3
: glutamate and glutamine metabolism,
methylaspartate cycle
: Glyoxylate and dicarboxylate metabolism,
C5-Branched dibasic acid metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: methylaspartate cycle,
L-glutamate degradation VI (to pyruvate)
: BR487show the reaction diagram
: R03696show the reaction diagram
: METHYLASPARTATE-AMMONIA-LYASE-RXNshow the reaction diagram
-
-
-
-
natural substrates
L-lactate dehydrogenase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
D-lactate dehydrogenase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
malate dehydrogenase [NAD(P)+]
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
L-2-hydroxycarboxylate dehydrogenase (NAD+)
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
malate dehydrogenase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
malate dehydrogenase (oxaloacetate-decarboxylating)
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
hydroxypyruvate reductase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
malate dehydrogenase (NADP+)
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
3-isopropylmalate dehydrogenase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
phosphoglycerate dehydrogenase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
diiodophenylpyruvate reductase
(S)-malate + NAD+ = oxaloacetate + NADH + H+
: alanine metabolism,
citric acid cycle,
C4 and CAM-carbon fixation,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation in photosynthetic organisms,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
C4 photosynthetic carbon assimilation cycle, NAD-ME type,
pyruvate fermentation to propanoate I,
TCA cycle III (animals),
formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
gluconeogenesis I,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, cytosol),
reductive TCA cycle II,
incomplete reductive TCA cycle,
gluconeogenesis III,
glyoxylate cycle,
mixed acid fermentation,
malate/L-aspartate shuttle pathway
: BR29300show the reaction diagram, BS188027show the reaction diagram
: R00342show the reaction diagram
: MALATE-DEH-RXNshow the reaction diagram, RXN-10813_WOPThis reaction also exists with phosphate.show the reaction diagram
: 113
-
-
-
-
natural substrates
malyl-CoA lyase
(S)-malyl-CoA = acetyl-CoA + glyoxylate
: ethylmalonyl-CoA pathway,
methylaspartate cycle
: Glyoxylate and dicarboxylate metabolism,
Methane metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: formaldehyde assimilation I (serine pathway),
methylaspartate cycle,
3-hydroxypropanoate cycle,
ethylmalonyl-CoA pathway
: BR3371show the reaction diagram, BS444081show the reaction diagram
: R00473show the reaction diagram
: MALYL-COA-LYASE-RXNshow the reaction diagram
: 905
-
-
-
-
natural substrates
acetyl-CoA carboxylase
ATP + propanoyl-CoA + HCO3- + H+ = ADP + phosphate + (S)-methylmalonyl-CoA
: CO2 fixation in Crenarchaeota,
methylaspartate cycle
: Valine, leucine and isoleucine degradation,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: 3-hydroxypropanoate/4-hydroxybutanate cycle,
methylaspartate cycle,
3-hydroxypropanoate cycle,
anaerobic energy metabolism (invertebrates, mitochondrial),
propanoyl CoA degradation I
: BR155show the reaction diagram
: R01859show the reaction diagram
: PROPIONYL-COA-CARBOXY-RXNshow the reaction diagram
: 1929
-
-
-
: possibly two-step reaction (similar to R00742 or R04385+R04386)
natural substrates
propionyl-CoA carboxylase
ATP + propanoyl-CoA + HCO3- + H+ = ADP + phosphate + (S)-methylmalonyl-CoA
: CO2 fixation in Crenarchaeota,
methylaspartate cycle
: Valine, leucine and isoleucine degradation,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: 3-hydroxypropanoate/4-hydroxybutanate cycle,
methylaspartate cycle,
3-hydroxypropanoate cycle,
anaerobic energy metabolism (invertebrates, mitochondrial),
propanoyl CoA degradation I
: BR155show the reaction diagram
: R01859show the reaction diagram
: PROPIONYL-COA-CARBOXY-RXNshow the reaction diagram
: 1929
-
-
-
: possibly two-step reaction (similar to R00742 or R04385+R04386)
natural substrates
methylmalonyl-CoA epimerase
(R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA
: CO2 fixation in Crenarchaeota,
propionate fermentation,
methylaspartate cycle
: Valine, leucine and isoleucine degradation,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
3-hydroxypropanoate/4-hydroxybutanate cycle,
pyruvate fermentation to propanoate I,
methylaspartate cycle,
3-hydroxypropanoate cycle,
anaerobic energy metabolism (invertebrates, mitochondrial),
propanoyl CoA degradation I
: BR204show the reaction diagram, BS970show the reaction diagram
: R02765show the reaction diagram
: METHYLMALONYL-COA-EPIM-RXNshow the reaction diagram
: 2642
-
-
-
-
natural substrates
acetate-CoA ligase (ADP-forming)
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle III (animals),
methylaspartate cycle,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, mitochondrial),
reductive TCA cycle II,
incomplete reductive TCA cycle,
pyruvate fermentation to acetate VI,
pyruvate fermentation to acetate V
: BR88show the reaction diagram
: R00405show the reaction diagram
: SUCCCOASYN-RXNshow the reaction diagram
: 260
-
-
-
-
natural substrates
succinate-CoA ligase (GDP-forming)
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle III (animals),
methylaspartate cycle,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, mitochondrial),
reductive TCA cycle II,
incomplete reductive TCA cycle,
pyruvate fermentation to acetate VI,
pyruvate fermentation to acetate V
: BR88show the reaction diagram
: R00405show the reaction diagram
: SUCCCOASYN-RXNshow the reaction diagram
: 260
-
-
-
-
natural substrates
succinate-CoA ligase (ADP-forming)
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: reductive TCA cycle I,
TCA cycle VIII (Chlamydia),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle III (animals),
methylaspartate cycle,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
anaerobic energy metabolism (invertebrates, mitochondrial),
reductive TCA cycle II,
incomplete reductive TCA cycle,
pyruvate fermentation to acetate VI,
pyruvate fermentation to acetate V
: BR88show the reaction diagram
: R00405show the reaction diagram
: SUCCCOASYN-RXNshow the reaction diagram
: 260
-
-
-
-
natural substrates
citrate (Si)-synthase
acetyl-CoA + H2O + oxaloacetate = citrate + CoA
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Glyoxylate and dicarboxylate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: nitrogen remobilization from senescing leaves,
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle VII (acetate-producers),
partial TCA cycle (obligate autotrophs),
TCA cycle III (animals),
methylaspartate cycle,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
ethene biosynthesis V (engineered),
glyoxylate cycle,
mixed acid fermentation,
TCA cycle VI (Helicobacter)
: BR44118show the reaction diagram
: R00351show the reaction diagram
: CITSYN-RXNshow the reaction diagram
: 267
-
-
-
: (pro-S)-carboxymethyl-forming (ec 2.3.3.1) (pro-R)-carboxymethyl-forming (ec 2.3.3.3) unknown stereospecificity (ec 2.3.3.16)
: The mammalian citrate synthase is located solely in the mitochondrial matrix. Citrate enters the mitochondrial matrix to react with the enzyme. Experiments done in rat liver indicate that this reaction is physiologically irreversible [7060582]. The reaction occurs in peroxisome in fungi [1897942] and plants [15923350] and in bacterial cytosol [4211224].
natural substrates
homocitrate synthase
acetyl-CoA + H2O + oxaloacetate = citrate + CoA
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Glyoxylate and dicarboxylate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: nitrogen remobilization from senescing leaves,
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle VII (acetate-producers),
partial TCA cycle (obligate autotrophs),
TCA cycle III (animals),
methylaspartate cycle,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
ethene biosynthesis V (engineered),
glyoxylate cycle,
mixed acid fermentation,
TCA cycle VI (Helicobacter)
: BR44118show the reaction diagram
: R00351show the reaction diagram
: CITSYN-RXNshow the reaction diagram
: 267
-
-
-
: (pro-S)-carboxymethyl-forming (ec 2.3.3.1) (pro-R)-carboxymethyl-forming (ec 2.3.3.3) unknown stereospecificity (ec 2.3.3.16)
: The mammalian citrate synthase is located solely in the mitochondrial matrix. Citrate enters the mitochondrial matrix to react with the enzyme. Experiments done in rat liver indicate that this reaction is physiologically irreversible [7060582]. The reaction occurs in peroxisome in fungi [1897942] and plants [15923350] and in bacterial cytosol [4211224].
natural substrates
citrate synthase (unknown stereospecificity)
acetyl-CoA + H2O + oxaloacetate = citrate + CoA
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Glyoxylate and dicarboxylate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: nitrogen remobilization from senescing leaves,
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle VII (acetate-producers),
partial TCA cycle (obligate autotrophs),
TCA cycle III (animals),
methylaspartate cycle,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
ethene biosynthesis V (engineered),
glyoxylate cycle,
mixed acid fermentation,
TCA cycle VI (Helicobacter)
: BR44118show the reaction diagram
: R00351show the reaction diagram
: CITSYN-RXNshow the reaction diagram
: 267
-
-
-
: (pro-S)-carboxymethyl-forming (ec 2.3.3.1) (pro-R)-carboxymethyl-forming (ec 2.3.3.3) unknown stereospecificity (ec 2.3.3.16)
: The mammalian citrate synthase is located solely in the mitochondrial matrix. Citrate enters the mitochondrial matrix to react with the enzyme. Experiments done in rat liver indicate that this reaction is physiologically irreversible [7060582]. The reaction occurs in peroxisome in fungi [1897942] and plants [15923350] and in bacterial cytosol [4211224].
natural substrates
citrate (Re)-synthase
acetyl-CoA + H2O + oxaloacetate = citrate + CoA
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Glyoxylate and dicarboxylate metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: nitrogen remobilization from senescing leaves,
TCA cycle IV (2-oxoglutarate decarboxylase),
TCA cycle V (2-oxoglutarate synthase),
TCA cycle VII (acetate-producers),
partial TCA cycle (obligate autotrophs),
TCA cycle III (animals),
methylaspartate cycle,
TCA cycle II (plants and fungi),
TCA cycle I (prokaryotic),
ethene biosynthesis V (engineered),
glyoxylate cycle,
mixed acid fermentation,
TCA cycle VI (Helicobacter)
: BR44118show the reaction diagram
: R00351show the reaction diagram
: CITSYN-RXNshow the reaction diagram
: 267
-
-
-
: (pro-S)-carboxymethyl-forming (ec 2.3.3.1) (pro-R)-carboxymethyl-forming (ec 2.3.3.3) unknown stereospecificity (ec 2.3.3.16)
: The mammalian citrate synthase is located solely in the mitochondrial matrix. Citrate enters the mitochondrial matrix to react with the enzyme. Experiments done in rat liver indicate that this reaction is physiologically irreversible [7060582]. The reaction occurs in peroxisome in fungi [1897942] and plants [15923350] and in bacterial cytosol [4211224].
natural substrates
succinate dehydrogenase
succinate + a quinone = fumarate + a quinol
: citric acid cycle,
methylaspartate cycle
: Citrate cycle (TCA cycle),
Pyruvate metabolism,
Butanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism
: BR49374show the reaction diagram
: R02164show the reaction diagram
-
-
-
: electron transport complex II
natural substrates, multi-step reaction
(3S)-malyl-CoA thioesterase
(S)-malyl-CoA + H2O = (S)-malate + CoA
: methylaspartate cycle
: Glyoxylate and dicarboxylate metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: methylaspartate cycle
: BR50984show the reaction diagram
: R10612show the reaction diagram
: RXN-14937show the reaction diagram
: 15625, 15660
-
-
-
-
natural substrates
methylmalonyl-CoA mutase
(R)-methylmalonyl-CoA = succinyl-CoA
: CO2 fixation in Crenarchaeota,
propionate fermentation,
methylaspartate cycle
: Valine, leucine and isoleucine degradation,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
3-hydroxypropanoate/4-hydroxybutanate cycle,
pyruvate fermentation to propanoate I,
methylaspartate cycle,
3-hydroxypropanoate cycle,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
anaerobic energy metabolism (invertebrates, mitochondrial),
propanoyl CoA degradation I,
conversion of succinate to propanoate
: BR249show the reaction diagram, BS380077show the reaction diagram, BS390473show the reaction diagram
: R00833show the reaction diagram
: METHYLMALONYL-COA-MUT-RXNshow the reaction diagram
: 10453, 1174
-
-
-
-
natural substrates
ethylmalonyl-CoA mutase
(R)-methylmalonyl-CoA = succinyl-CoA
: CO2 fixation in Crenarchaeota,
propionate fermentation,
methylaspartate cycle
: Valine, leucine and isoleucine degradation,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
3-hydroxypropanoate/4-hydroxybutanate cycle,
pyruvate fermentation to propanoate I,
methylaspartate cycle,
3-hydroxypropanoate cycle,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
anaerobic energy metabolism (invertebrates, mitochondrial),
propanoyl CoA degradation I,
conversion of succinate to propanoate
: BR249show the reaction diagram, BS380077show the reaction diagram, BS390473show the reaction diagram
: R00833show the reaction diagram
: METHYLMALONYL-COA-MUT-RXNshow the reaction diagram
: 10453, 1174
-
-
-
-
natural substrates
2-hydroxyisobutanoyl-CoA mutase
(R)-methylmalonyl-CoA = succinyl-CoA
: CO2 fixation in Crenarchaeota,
propionate fermentation,
methylaspartate cycle
: Valine, leucine and isoleucine degradation,
Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,
3-hydroxypropanoate/4-hydroxybutanate cycle,
pyruvate fermentation to propanoate I,
methylaspartate cycle,
3-hydroxypropanoate cycle,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
anaerobic energy metabolism (invertebrates, mitochondrial),
propanoyl CoA degradation I,
conversion of succinate to propanoate
: BR249show the reaction diagram, BS380077show the reaction diagram, BS390473show the reaction diagram
: R00833show the reaction diagram
: METHYLMALONYL-COA-MUT-RXNshow the reaction diagram
: 10453, 1174
-
-
-
-
natural substrates
succinyl-CoA:mesaconate CoA transferase
mesaconate + succinyl-CoA = 2-methylfumaryl-CoA + succinate
: methylaspartate cycle
: Glyoxylate and dicarboxylate metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: methylaspartate cycle
: BR52650show the reaction diagram
: R10904show the reaction diagram
: RXN-12168show the reaction diagram
-
-
-
-
natural substrates