Print
carboxylesterase
Pathways
lipid metabolism (BRENDA)
:= BRENDA, 
:= KEGG, 
:= MetaCyc, 
:= SABIO-RK
:= amino acid sequences 
:= show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
palmitoyl-CoA + H2O = CoA + palmitate
; "show the reaction diagram")
; "show the reaction diagram")
; "show the reaction diagram")
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natural substrates
acylglycerol lipase
palmitoyl-CoA + H2O = CoA + palmitate
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natural substrates
lysophospholipase
palmitoyl-CoA + H2O = CoA + palmitate
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natural substrates
palmitoyl-CoA + H2O = CoA + palmitate
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natural substrates
acetyl-CoA hydrolase
palmitoyl-CoA + H2O = CoA + palmitate
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natural substrates
palmitoyl-CoA hydrolase
palmitoyl-CoA + H2O = CoA + palmitate
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natural substrates
acyl-CoA hydrolase
palmitoyl-CoA + H2O = CoA + palmitate
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natural substrates
palmitoyl[protein] hydrolase
palmitoyl-CoA + H2O = CoA + palmitate
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natural substrates
phenylacetyl-CoA hydrolase
palmitoyl-CoA + H2O = CoA + palmitate
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natural substrates
acetyl-CoA C-acyltransferase
palmitoyl-CoA + H2O = CoA + palmitate
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natural substrates
acetyl-CoA hydrolase
n-butyryl-CoA + H2O = CoA + n-butanoate
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palmitoyl-CoA hydrolase
n-butyryl-CoA + H2O = CoA + n-butanoate
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acyl-CoA hydrolase
n-butyryl-CoA + H2O = CoA + n-butanoate
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4-hydroxybenzoyl-CoA thioesterase
n-butyryl-CoA + H2O = CoA + n-butanoate
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phenylacetyl-CoA hydrolase
n-butyryl-CoA + H2O = CoA + n-butanoate
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4-acetamidobutyryl-CoA deacetylase
n-butyryl-CoA + H2O = CoA + n-butanoate
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acetyl-CoA C-acyltransferase
n-butyryl-CoA + H2O = CoA + n-butanoate
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acetyl-CoA C-acyltransferase
hexanoyl-CoA + H2O = CoA + hexanoate
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acetyl-CoA hydrolase
hexanoyl-CoA + H2O = CoA + hexanoate
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palmitoyl-CoA hydrolase
hexanoyl-CoA + H2O = CoA + hexanoate
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acyl-CoA hydrolase
hexanoyl-CoA + H2O = CoA + hexanoate
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4-hydroxybenzoyl-CoA thioesterase
hexanoyl-CoA + H2O = CoA + hexanoate
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phenylacetyl-CoA hydrolase
hexanoyl-CoA + H2O = CoA + hexanoate
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long-chain-fatty-acid-CoA ligase
ATP + palmitoleate + CoA = AMP + diphosphate + palmitoleoyl-CoA
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natural substrates
short-chain acyl-CoA dehydrogenase
butyryl-CoA + acceptor = but-2-enoyl-CoA + reduced acceptor
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isovaleryl-CoA dehydrogenase
butyryl-CoA + acceptor = but-2-enoyl-CoA + reduced acceptor
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short-chain 2-methylacyl-CoA dehydrogenase
butyryl-CoA + acceptor = but-2-enoyl-CoA + reduced acceptor
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medium-chain acyl-CoA dehydrogenase
butyryl-CoA + acceptor = but-2-enoyl-CoA + reduced acceptor
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acyl-CoA oxidase
palmitoyl-CoA + O2 = 2-trans-hexadecenoyl-CoA + H2O2
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medium-chain acyl-CoA dehydrogenase
hexadecanoyl-CoA + acceptor = 2-hexadecenoyl-CoA + reduced acceptor
; "show the reaction diagram")
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: incomplete reactionnatural substrates
long-chain acyl-CoA dehydrogenase
hexadecanoyl-CoA + acceptor = 2-hexadecenoyl-CoA + reduced acceptor
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: incomplete reactionnatural substrates
hexadecanoyl-CoA + acceptor = 2-hexadecenoyl-CoA + reduced acceptor
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: incomplete reactionnatural substrates
DELTA3-DELTA2-enoyl-CoA isomerase
3-trans-Hexadecenoyl-CoA = 2-trans-Hexadecenoyl-CoA
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acyl-CoA oxidase
butyryl-CoA + O2 = trans-2-butenoyl-CoA + H2O2
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short-chain acyl-CoA dehydrogenase
butyryl-CoA + O2 = trans-2-butenoyl-CoA + H2O2
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short-chain acyl-CoA dehydrogenase
2-butenoyl-CoA + reduced electron transfer flavoprotein = butanoyl-CoA + electron transfer protein
generic compounds
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natural substrates
oxepin-CoA hydrolase
(R)-3-hydroxybutyryl-CoA = trans-2-butenoyl-CoA + H2O
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natural substrates
acetoacetyl-CoA reductase
(R)-3-hydroxybutyryl-CoA = trans-2-butenoyl-CoA + H2O
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natural substrates
acetate-CoA ligase
ATP + butyrate + CoA = AMP + diphosphate + butyryl-CoA
; "show the reaction diagram")
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natural substrates
propionate-CoA ligase
ATP + butyrate + CoA = AMP + diphosphate + butyryl-CoA
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natural substrates
medium-chain acyl-CoA ligase
ATP + butyrate + CoA = AMP + diphosphate + butyryl-CoA
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natural substrates
long-chain-fatty-acid-CoA ligase
ATP + butyrate + CoA = AMP + diphosphate + butyryl-CoA
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natural substrates
phenylacetate-CoA ligase
ATP + butyrate + CoA = AMP + diphosphate + butyryl-CoA
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natural substrates
3-hydroxypropionyl-CoA synthase
ATP + butyrate + CoA = AMP + diphosphate + butyryl-CoA
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natural substrates
3-(methylthio)propionyl-CoA ligase
ATP + butyrate + CoA = AMP + diphosphate + butyryl-CoA
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natural substrates
acetoacetyl-CoA reductase
(R)-3-hydroxybutyryl-CoA + NADPH + H+ = 3-oxobutyryl-CoA + NADP+
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natural substrates
galactolipase
phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate
; "show the reaction diagram")
; "show the reaction diagram")
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natural substrates
phospholipase A1
phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate
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natural substrates
phospholipase A2
phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate
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natural substrates
lysophospholipase
phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate
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natural substrates
20alpha-hydroxysteroid dehydrogenase
sn-glycerol 3-phosphate + NADP+ = D-glyceraldehyde 3-phosphate + NADPH + H+
; "show the reaction diagram")
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natural substrates
glycerol-3-phosphate 1-dehydrogenase (NADP+)
sn-glycerol 3-phosphate + NADP+ = D-glyceraldehyde 3-phosphate + NADPH + H+
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natural substrates
alcohol dehydrogenase (NADP+)
sn-glycerol 3-phosphate + NADP+ = D-glyceraldehyde 3-phosphate + NADPH + H+
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natural substrates
aldose reductase
sn-glycerol 3-phosphate + NADP+ = D-glyceraldehyde 3-phosphate + NADPH + H+
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natural substrates
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
sn-glycerol 3-phosphate + NADP+ = D-glyceraldehyde 3-phosphate + NADPH + H+
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natural substrates
acylglycerol lipase
CnHmCO-C3O3H7 + H2O = CnHmCO2H + glycerol
; "show the reaction diagram")
; "show the reaction diagram")
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: see R01352 (2-acyl type reaction)natural substrates
triacylglycerol lipase
CnHmCO-C3O3H7 + H2O = CnHmCO2H + glycerol
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: see R01352 (2-acyl type reaction)natural substrates
fatty-acyl-ethyl-ester synthase
CnHmCO-C3O3H7 + H2O = CnHmCO2H + glycerol
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: see R01352 (2-acyl type reaction)natural substrates
hormone-sensitive lipase
CnHmCO-C3O3H7 + H2O = CnHmCO2H + glycerol
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: see R01352 (2-acyl type reaction)natural substrates
sterol esterase
triacylglycerol + H2O = diacylglycerol + a carboxylate
; "show the reaction diagram")
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: general reaction also hydrolyzing at sn-1 positionnatural substrates, generic
triacylglycerol lipase
triacylglycerol + H2O = diacylglycerol + a carboxylate
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: general reaction also hydrolyzing at sn-1 positionnatural substrates, generic
phospholipase A1
triacylglycerol + H2O = diacylglycerol + a carboxylate
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: general reaction also hydrolyzing at sn-1 positionnatural substrates, generic
lipoprotein lipase
triacylglycerol + H2O = diacylglycerol + a carboxylate
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: general reaction also hydrolyzing at sn-1 positionnatural substrates, generic
hormone-sensitive lipase
triacylglycerol + H2O = diacylglycerol + a carboxylate
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: general reaction also hydrolyzing at sn-1 positionnatural substrates, generic
triacylglycerol lipase
diacylglycerol + H2O = monoacylglycerol + a carboxylate
; "show the reaction diagram")
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natural substrates, generic
hormone-sensitive lipase
diacylglycerol + H2O = monoacylglycerol + a carboxylate
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natural substrates, generic
2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate + reduced acceptor = 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate + acceptor
; "show the reaction diagram")
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natural substrates, generic
alditol + NAD+ = aldose + NADH + H+
; "show the reaction diagram")
: ALDEHYDE-REDUCTASE-RXN_WOP
This reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
indanol dehydrogenase
alditol + NAD+ = aldose + NADH + H+
: ALDEHYDE-REDUCTASE-RXN_WOPThis reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
alcohol dehydrogenase (NADP+)
alditol + NAD+ = aldose + NADH + H+
: ALDEHYDE-REDUCTASE-RXN_WOPThis reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
1,3-propanediol dehydrogenase
alditol + NAD+ = aldose + NADH + H+
: ALDEHYDE-REDUCTASE-RXN_WOPThis reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
aldose reductase
alditol + NAD+ = aldose + NADH + H+
: ALDEHYDE-REDUCTASE-RXN_WOPThis reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
3-methylbutanal reductase
alditol + NAD+ = aldose + NADH + H+
: ALDEHYDE-REDUCTASE-RXN_WOPThis reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
D-xylose reductase [NAD(P)H]
alditol + NAD+ = aldose + NADH + H+
: ALDEHYDE-REDUCTASE-RXN_WOPThis reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
galactitol 2-dehydrogenase (L-tagatose-forming)
alditol + NAD+ = aldose + NADH + H+
: ALDEHYDE-REDUCTASE-RXN_WOPThis reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
D-xylose reductase (NADH)
alditol + NAD+ = aldose + NADH + H+
: ALDEHYDE-REDUCTASE-RXN_WOPThis reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
glycerol dehydrogenase
alditol + NAD+ = aldose + NADH + H+
: ALDEHYDE-REDUCTASE-RXN_WOPThis reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
lactaldehyde reductase
alditol + NAD+ = aldose + NADH + H+
: ALDEHYDE-REDUCTASE-RXN_WOPThis reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
methylglyoxal reductase (NADH)
alditol + NAD+ = aldose + NADH + H+
: ALDEHYDE-REDUCTASE-RXN_WOPThis reaction also exists with phosphate., RXN-11709_WOPThis reaction also exists with phosphate.: 6774-
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: general reaction (see R01036, R01093 and R01758) NADP+ (see R02820)natural substrates
alditol + NADP+ = aldose + NADPH + H+
; "show the reaction diagram")
; "show the reaction diagram")
; "show the reaction diagram")
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
alcohol dehydrogenase
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
L-xylulose reductase
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
20alpha-hydroxysteroid dehydrogenase
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
glycerol 2-dehydrogenase (NADP+)
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
carbonyl reductase (NADPH)
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
prostaglandin-F synthase
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
glucuronate reductase
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
alcohol dehydrogenase (NADP+)
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
aldose reductase
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
3-methylbutanal reductase
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
methylglyoxal reductase (NADPH)
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
D-xylose reductase [NAD(P)H]
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
D-galacturonate reductase
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
D/L-glyceraldehyde reductase
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
D-xylose reductase (NADPH)
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
glycerol dehydrogenase
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
alcohol dehydrogenase [NAD(P)+]
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
glycerol dehydrogenase (NADP+)
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
alditol + NADP+ = aldose + NADPH + H+
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: NAD+ (see R01036); general reaction (see R01041, R01095, R01431, R01759 and R01787) NAD+ (see R02819)natural substrates
glycerol 2-dehydrogenase (NADP+)
sn-glycerol 1-phosphate + NADP+ = glycerone phosphate + NADPH + H+
; "show the reaction diagram")
; "show the reaction diagram")
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: NAD+ (see R00842); see NADH (R05679)natural substrates
indole-3-acetaldehyde reductase (NADPH)
sn-glycerol 1-phosphate + NADP+ = glycerone phosphate + NADPH + H+
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: NAD+ (see R00842); see NADH (R05679)natural substrates
alcohol dehydrogenase (NADP+)
sn-glycerol 1-phosphate + NADP+ = glycerone phosphate + NADPH + H+
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: NAD+ (see R00842); see NADH (R05679)natural substrates
aldose reductase
sn-glycerol 1-phosphate + NADP+ = glycerone phosphate + NADPH + H+
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: NAD+ (see R00842); see NADH (R05679)natural substrates
sn-glycerol-1-phosphate dehydrogenase
sn-glycerol 1-phosphate + NADP+ = glycerone phosphate + NADPH + H+
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: NAD+ (see R00842); see NADH (R05679)natural substrates
glucose-6-phosphate dehydrogenase (NADP+)
sn-glycerol 1-phosphate + NADP+ = glycerone phosphate + NADPH + H+
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: NAD+ (see R00842); see NADH (R05679)natural substrates
glycerol-3-phosphate dehydrogenase (NAD+)
sn-glycerol 1-phosphate + NADP+ = glycerone phosphate + NADPH + H+
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: NAD+ (see R00842); see NADH (R05679)natural substrates
glycerol-3-phosphate dehydrogenase [NAD(P)+]
sn-glycerol 1-phosphate + NADP+ = glycerone phosphate + NADPH + H+
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: NAD+ (see R00842); see NADH (R05679)natural substrates
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
sn-glycerol 1-phosphate + NADP+ = glycerone phosphate + NADPH + H+
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: NAD+ (see R00842); see NADH (R05679)natural substrates
archaetidylserine synthase
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol + L-serine = CMP + 2,3-bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
; "show the reaction diagram")
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natural substrates
phosphoglycerol geranylgeranyltransferase
geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + 3-(O-geranylgeranyl)-sn-glycerol 1-phosphate
; "show the reaction diagram")
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natural substrates
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
CTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate = diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
; "show the reaction diagram")
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natural substrates
geranylgeranylglycerol-phosphate geranylgeranyltransferase
geranylgeranyl diphosphate + 3-(O-geranylgeranyl)-sn-glycerol 1-phosphate = diphosphate + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
; "show the reaction diagram")
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natural substrates
CoA + apo-[acyl-carrier protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]
; "show the reaction diagram")
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natural substrates
holo-[acyl-carrier-protein] synthase
CoA + apo-[acyl-carrier protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]
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natural substrates
[acyl-carrier-protein] phosphodiesterase
holo-[acyl-carrier protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier protein]
; "show the reaction diagram")
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natural substrates, generic, protein
trans-2-decenoyl-[acyl-carrier protein] isomerase
a trans-dec-2-enoyl-[acyl-carrier protein] = a cis-dec-3-enoyl-[acyl-carrier protein]
; "show the reaction diagram")
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natural substrates
(3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl-carrier protein] + H2O
; "show the reaction diagram")
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: This enzyme is different from EC 4.2.1.60, since the later is specific for C10 chain length, and is used in the synthesis of unsaturated fatty acids, while this enzyme accepts a broad substrate range and is used in the synthesis of saturated fatty acids.natural substrates
fatty-acid synthase system
(3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl-carrier protein] + H2O
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: This enzyme is different from EC 4.2.1.60, since the later is specific for C10 chain length, and is used in the synthesis of unsaturated fatty acids, while this enzyme accepts a broad substrate range and is used in the synthesis of saturated fatty acids.natural substrates
fatty-acyl-CoA synthase system
(3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl-carrier protein] + H2O
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: This enzyme is different from EC 4.2.1.60, since the later is specific for C10 chain length, and is used in the synthesis of unsaturated fatty acids, while this enzyme accepts a broad substrate range and is used in the synthesis of saturated fatty acids.natural substrates
(3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl-carrier protein] + H2O
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: This enzyme is different from EC 4.2.1.60, since the later is specific for C10 chain length, and is used in the synthesis of unsaturated fatty acids, while this enzyme accepts a broad substrate range and is used in the synthesis of saturated fatty acids.natural substrates
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
(3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2-decenoyl-[acyl-carrier protein] + H2O
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: This enzyme is different from EC 4.2.1.60, since the later is specific for C10 chain length, and is used in the synthesis of unsaturated fatty acids, while this enzyme accepts a broad substrate range and is used in the synthesis of saturated fatty acids.natural substrates
a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = a 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
; "show the reaction diagram")
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: general reaction (see R04533, R04534, R04536, R04543, R04566, R04953, R04964 and R07763)natural substrates, generic, protein
3-oxoacyl-[acyl-carrier-protein] reductase
a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = a 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
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: general reaction (see R04533, R04534, R04536, R04543, R04566, R04953, R04964 and R07763)natural substrates, generic, protein
acyl-CoA oxidase
hexanoyl-CoA + O2 = (2E)-hex-2-enoyl-CoA + H2O2
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enoyl-[acyl-carrier-protein] reductase (NADH)
an acyl-[acyl-carrier protein] + NAD+ = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+
; "show the reaction diagram")
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natural substrates, generic, protein
DELTA3-DELTA2-enoyl-CoA isomerase
3-trans-Hexenoyl-CoA = 2-trans-Hexenoyl-CoA
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natural substrates
5.3.3.M5
3-trans-Hexenoyl-CoA = 2-trans-Hexenoyl-CoA
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natural substrates
long-chain-3-hydroxyacyl-CoA dehydrogenase
(S)-3-hydroxyhexanoyl-CoA + NAD+ = 3-oxohexanoyl-CoA + NADH + H+
; "show the reaction diagram")
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natural substrates
3-hydroxyacyl-CoA dehydrogenase
(S)-3-hydroxyhexanoyl-CoA + NAD+ = 3-oxohexanoyl-CoA + NADH + H+
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natural substrates
cyclopropane-fatty-acyl-phospholipid synthase
S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid
; "show the reaction diagram")
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natural substrates
acetyl-CoA carboxylase
ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA
; "show the reaction diagram")
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: two-step reaction (see R04385 + R04386)natural substrates
propionyl-CoA carboxylase
ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA
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: two-step reaction (see R04385 + R04386)natural substrates
methylcrotonoyl-CoA carboxylase
ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA
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: two-step reaction (see R04385 + R04386)natural substrates
malonyl-CoA + an [acyl-carrier protein] = CoA + a malonyl-[acyl-carrier protein]
; "show the reaction diagram")
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natural substrates
[acyl-carrier-protein] S-malonyltransferase
malonyl-CoA + an [acyl-carrier protein] = CoA + a malonyl-[acyl-carrier protein]
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natural substrates
fatty-acid synthase system
malonyl-CoA + an [acyl-carrier protein] = CoA + a malonyl-[acyl-carrier protein]
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natural substrates
fatty-acyl-CoA synthase system
malonyl-CoA + an [acyl-carrier protein] = CoA + a malonyl-[acyl-carrier protein]
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase III
acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2
; "show the reaction diagram")
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natural substrates
branched-chain beta-ketoacyl-[acyl-carrier-protein] synthase
acetyl-CoA + a malonyl-[acyl-carrier protein] = an acetoacetyl-[acyl-carrier protein] + CoA + CO2
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase I
a malonyl-[acyl-carrier protein] = an acetyl-[acyl-carrier protein] + CO2
; "show the reaction diagram")
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natural substrates
malonyl-S-ACP decarboxylase
a malonyl-[acyl-carrier protein] = an acetyl-[acyl-carrier protein] + CO2
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natural substrates
4.1.1.M15
a malonyl-[acyl-carrier protein] = an acetyl-[acyl-carrier protein] + CO2
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natural substrates
acetyl-CoA + an [acyl-carrier protein] = CoA + an acetyl-[acyl-carrier protein]
; "show the reaction diagram")
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natural substrates
beta-ketoacyl-[acyl-carrier-protein] synthase III
acetyl-CoA + an [acyl-carrier protein] = CoA + an acetyl-[acyl-carrier protein]
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natural substrates
[acyl-carrier-protein] S-acetyltransferase
acetyl-CoA + an [acyl-carrier protein] = CoA + an acetyl-[acyl-carrier protein]
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natural substrates
[acyl-carrier-protein] S-malonyltransferase
acetyl-CoA + an [acyl-carrier protein] = CoA + an acetyl-[acyl-carrier protein]
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natural substrates
fatty-acid synthase system
acetyl-CoA + an [acyl-carrier protein] = CoA + an acetyl-[acyl-carrier protein]
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natural substrates
fatty-acyl-CoA synthase system
acetyl-CoA + an [acyl-carrier protein] = CoA + an acetyl-[acyl-carrier protein]
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natural substrates
holo-[acyl-carrier-protein] synthase
acetyl-CoA + an [acyl-carrier protein] = CoA + an acetyl-[acyl-carrier protein]
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natural substrates
2-monoacylglycerol = 1-monoacylglycerol
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natural substrates, generic
0.0.0.0
spontaneous reaction
2-monoacylglycerol = 1-monoacylglycerol
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natural substrates, generic
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]
2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate + 8 NADP+ = 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate + 8 NADPH + 8 H+
; "show the reaction diagram")
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natural substrates
archaetidylserine synthase
CDP-2,3-bis-(O-phytanyl)-sn-glycerol + L-serine = CMP + 2,3-bis-(O-phytanyl)-sn-glycero-1-phospho-L-serine
; "show the reaction diagram")
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natural substrates
inositol-3-phosphate synthase
CDP-2,3-bis-(O-phytanyl)-sn-glycerol + 1L-myo-inositol 1-phosphate = CMP + 1-archaetidyl-1D-myo-inositol 3-phosphate
; "show the reaction diagram")
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natural substrates
archaetidylinositol phosphate synthase
CDP-2,3-bis-(O-phytanyl)-sn-glycerol + 1L-myo-inositol 1-phosphate = CMP + 1-archaetidyl-1D-myo-inositol 3-phosphate
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natural substrates
phosphatidylinositol phosphate synthase
CDP-2,3-bis-(O-phytanyl)-sn-glycerol + 1L-myo-inositol 1-phosphate = CMP + 1-archaetidyl-1D-myo-inositol 3-phosphate
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natural substrates
archaetidylinositol phosphate phosphatase
1-archaetidyl-1D-myo-inositol 3-phosphate + H2O = 1-archaetidyl-1D-myo-inositol + phosphate
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natural substrates
UDP-alpha-D-glucose + archaeol = UDP + 1,2-bis-phytanyl-sn-glycero-3-O-beta-D-glucoside
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natural substrates
monoglucosylarchaeol synthase
UDP-alpha-D-glucose + archaeol = UDP + 1,2-bis-phytanyl-sn-glycero-3-O-beta-D-glucoside
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natural substrates
UDP-alpha-D-glucose + 1,2-diphytanyl-sn-glycero-3-O-beta-D-glucoside = UDP + 1,2-diphytanyl-sn-glycero-3-O-(6-O-beta-D-glucosyl)-beta-D-glucoside
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natural substrates
diglucosylarchaeol synthase
UDP-alpha-D-glucose + 1,2-diphytanyl-sn-glycero-3-O-beta-D-glucoside = UDP + 1,2-diphytanyl-sn-glycero-3-O-(6-O-beta-D-glucosyl)-beta-D-glucoside
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natural substrates
carboxylic acid-CoA ligase (GDP-forming)
GTP + butyrate + CoA = GDP + phosphate + butyryl-CoA
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acetate-CoA ligase (ADP-forming)
ADP + phosphate + butyryl-CoA = ATP + butyrate + CoA
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succinate-CoA ligase (ADP-forming)
ADP + phosphate + butyryl-CoA = ATP + butyrate + CoA
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4-hydroxybutyrate-CoA ligase (ADP-forming)
ADP + phosphate + butyryl-CoA = ATP + butyrate + CoA
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malate-CoA ligase
ADP + phosphate + butyryl-CoA = ATP + butyrate + CoA
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carboxylic acid-CoA ligase (NDP-forming)
ADP + phosphate + butyryl-CoA = ATP + butyrate + CoA
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meromycolic acid enoyl-[acyl-carrier-protein] reductase
trans-2-hexadecenoyl-CoA + NADH = hexadecanoyl-CoA + NAD+
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trans-2-enoyl-CoA reductase (NADPH)
trans-2-hexadecenoyl-CoA + NADH = hexadecanoyl-CoA + NAD+
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trans-2-enoyl-CoA reductase (NAD+)
trans-2-hexadecenoyl-CoA + NADH = hexadecanoyl-CoA + NAD+
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enoyl-[acyl-carrier-protein] reductase (NADH)
trans-2-hexadecenoyl-CoA + NADH = hexadecanoyl-CoA + NAD+
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enoyl-[acyl-carrier-protein] reductase (NADPH)
2-trans-hexadecenoyl-CoA + NADPH = hexadecanoyl CoA + NADP+
; "show the reaction diagram")
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natural substrates
trans-2-enoyl-CoA reductase (NADPH)
2-trans-hexadecenoyl-CoA + NADPH = hexadecanoyl CoA + NADP+
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natural substrates
acyl-CoA dehydrogenase (NADP+)
2-trans-hexadecenoyl-CoA + NADPH = hexadecanoyl CoA + NADP+
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natural substrates
very-long-chain enoyl-CoA reductase
2-trans-hexadecenoyl-CoA + NADPH = hexadecanoyl CoA + NADP+
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natural substrates
2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
trans-trans-2,4-hexadecadienoyl-CoA + NADPH = trans-2-hexadecenoyl-CoA + NADP+
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natural substrates
acetate-CoA ligase
ATP + a medium-chain fatty acid + CoA = AMP + diphosphate + a medium-chain acyl-CoA
; "show the reaction diagram")
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: general reactionnatural substrates
4-coumarate-CoA ligase
ATP + a medium-chain fatty acid + CoA = AMP + diphosphate + a medium-chain acyl-CoA
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: general reactionnatural substrates
medium-chain acyl-CoA ligase
ATP + a medium-chain fatty acid + CoA = AMP + diphosphate + a medium-chain acyl-CoA
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: general reactionnatural substrates
long-chain-fatty-acid-CoA ligase
ATP + a medium-chain fatty acid + CoA = AMP + diphosphate + a medium-chain acyl-CoA
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: general reactionnatural substrates
3-(methylthio)propionyl-CoA ligase
ATP + a medium-chain fatty acid + CoA = AMP + diphosphate + a medium-chain acyl-CoA
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: general reactionnatural substrates
short-chain-enoyl-CoA hydratase
trans-2-hexenoyl-CoA + H2O = (3S)-3-hydroxyhexanoyl-CoA
; "show the reaction diagram")
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natural substrates
enoyl-CoA hydratase
trans-2-hexenoyl-CoA + H2O = (3S)-3-hydroxyhexanoyl-CoA
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natural substrates
medium-chain-enoyl-CoA hydratase
trans-2-hexenoyl-CoA + H2O = (3S)-3-hydroxyhexanoyl-CoA
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natural substrates