Pathways
ketogluconate metabolism (BRENDA)
:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
L-idonate + NAD+ = 5-dehydro-D-gluconate + NADH + H+
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: see R05684 (NADPH)
: The enzyme from Escherichia coli cannot oxidize D-gluconate to form 5-dehydrogluconate, a reaction that is catalyzed by EC 1.1.1.69, gluconate 5-dehydrogenase.
natural substrates
L-idonate 5-dehydrogenase
L-idonate + NAD+ = 5-dehydro-D-gluconate + NADH + H+
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-
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: see R05684 (NADPH)
: The enzyme from Escherichia coli cannot oxidize D-gluconate to form 5-dehydrogluconate, a reaction that is catalyzed by EC 1.1.1.69, gluconate 5-dehydrogenase.
natural substrates
L-idonate 5-dehydrogenase (NAD+)
L-idonate + NAD+ = 5-dehydro-D-gluconate + NADH + H+
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-
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: see R05684 (NADPH)
: The enzyme from Escherichia coli cannot oxidize D-gluconate to form 5-dehydrogluconate, a reaction that is catalyzed by EC 1.1.1.69, gluconate 5-dehydrogenase.
natural substrates
2-dehydro-L-gulonate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
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natural substrates
2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
2-dehydro-L-gulonate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
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natural substrates
2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
2-dehydro-L-gulonate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
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natural substrates
gluconate 2-dehydrogenase
D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+
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natural substrates
2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+
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natural substrates
phosphogluconate 2-dehydrogenase
D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+
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natural substrates
hydroxypyruvate reductase
D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+
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natural substrates
gluconokinase
ATP + D-gluconate = ADP + 6-phospho-D-gluconate
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natural substrates
2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
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natural substrates
2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
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natural substrates
L-idonate + NADP+ = 2-keto-L-idonate + NADPH
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natural substrates
gluconate 2-dehydrogenase
L-idonate + NADP+ = 2-keto-L-idonate + NADPH
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natural substrates
D-2-hydroxyacid dehydrogenase (NADP+)
L-idonate + NADP+ = 2-keto-L-idonate + NADPH
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natural substrates
2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
L-idonate + NADP+ = 2-keto-L-idonate + NADPH
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natural substrates
L-idonate 5-dehydrogenase
L-idonate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+
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: see R05683 (NADH)
: The enzyme from Escherichia coli cannot oxidize D-gluconate to form 5-dehydrogluconate, a reaction that is catalyzed by EC 1.1.1.69, gluconate 5-dehydrogenase.
natural substrates
gluconate 2-dehydrogenase (acceptor)
D-gluconate + FAD = 2-dehydro-D-gluconate + FADH2
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natural substrates
2,5-diketo-D-gluconate + NADPH = 5-keto-D-gluconate + NADP+
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natural substrates
gluconate 2-dehydrogenase
2,5-diketo-D-gluconate + NADPH = 5-keto-D-gluconate + NADP+
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natural substrates
2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
2,5-diketo-D-gluconate + NADPH = 5-keto-D-gluconate + NADP+
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natural substrates
D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+
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: NAD+ (see R01738)
natural substrates
gluconate 2-dehydrogenase
D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+
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: NAD+ (see R01738)
natural substrates
gluconate 5-dehydrogenase
D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+
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: NAD+ (see R01738)
natural substrates
dehydrogluconate dehydrogenase
2-dehydro-D-gluconate + acceptor = 2,5-didehydro-D-gluconate + reduced acceptor
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natural substrates, generic