Pathways

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BRENDA KEGG MetaCyc

isoprenoid biosynthesis (BRENDA)

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
cyclooctat-9-en-7-ol synthase
geranylgeranyl diphosphate + H2O = cyclooctat-9-en-7-ol + diphosphate
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natural substrates
geranylgeranyl diphosphate reductase
phytyl diphosphate + 3 NADP+ = geranylgeranyl diphosphate + 3 NADPH + 3 H+
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: three-step reaction see R08754+R08755+R08756
natural substrates
geranylgeranyl phosphate kinase
ATP + geranylgeranyl phosphate = ADP + geranylgeranyl diphosphate
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natural substrates
farnesol kinase
ATP + geranylgeraniol = ADP + geranylgeranyl phosphate
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natural substrates
undecaprenol kinase
ATP + geranylgeraniol = ADP + geranylgeranyl phosphate
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natural substrates
geranylgeraniol kinase
ATP + geranylgeraniol = ADP + geranylgeranyl phosphate
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natural substrates
tritrans,polycis-undecaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
geranylgeranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + tritrans,heptacis-undecaprenyl diphosphate
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natural substrates
all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]
geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate
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: 5-step reaction see R07475+R05613+R05612+R05611+R07267
natural substrates
all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate
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: 5-step reaction see R07475+R05613+R05612+R05611+R07267
natural substrates
(2E,6E)-farnesyl-diphosphate all-trans-nonaprenyl diphosphate synthase
geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate
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: 5-step reaction see R07475+R05613+R05612+R05611+R07267
natural substrates
all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]
geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate
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: 7-step reaction see R02003+R02061+R07475+R05613+R05612+R05611+R07267
natural substrates
(2E,6E)-farnesyl-diphosphate all-trans-nonaprenyl diphosphate synthase
geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate
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: 7-step reaction see R02003+R02061+R07475+R05613+R05612+R05611+R07267
natural substrates
all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]
(2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate = 6 diphosphate + all-trans-nonaprenyl diphosphate
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natural substrates, generic, polymer
all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
(2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate = 6 diphosphate + all-trans-nonaprenyl diphosphate
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natural substrates, generic, polymer
ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific]
(2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate = 6 diphosphate + all-trans-nonaprenyl diphosphate
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natural substrates, generic, polymer
(2E,6E)-farnesyl-diphosphate all-trans-nonaprenyl diphosphate synthase
(2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate = 6 diphosphate + all-trans-nonaprenyl diphosphate
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natural substrates, generic, polymer
4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NADPH = dimethylallyl diphosphate + isopentenyl diphosphate + NADP+ + H2O
incomplete
O7P2C5H12
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(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced ferredoxin + 2 H+
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natural substrates, generic, protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + CMP
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natural substrates
ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific]
(2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate
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: 7-step reaction see R02061+R07475+R05613+R05612+R05611+R07267+R08747
natural substrates
all-trans-decaprenyl-diphosphate synthase
(2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate
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: 7-step reaction see R02061+R07475+R05613+R05612+R05611+R07267+R08747
natural substrates
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = ADP + 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
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natural substrates
1-deoxy-D-xylulose-5-phosphate reductoisomerase
2-C-Methyl-D-erythritol 4-phosphate + NADP+ <=> 1-Deoxy-D-xylulose 5-phosphate + NADPH + H+
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natural substrates
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
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natural substrates
hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate
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: 2-step reaction see R07475+R05613
natural substrates
trifunctional (all-E)-isoprenyl diphospate synthase
geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate
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: 2-step reaction see R07475+R05613
natural substrates
heptaprenyl diphosphate synthase
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate
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: 4-step reaction see R02061+R07475+R05613+R05612
natural substrates
trifunctional (all-E)-isoprenyl diphospate synthase
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate
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: 4-step reaction see R02061+R07475+R05613+R05612
natural substrates
lycopaoctaene synthase
2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate
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: a part of multi-step reaction (see R07916, R02065+R07270) subsequently R07270 a part of multi-step reaction (see R10177, R02065+R04218) a part of multi-step reaction (see R12281, R02065+R12280)
natural substrates
15-cis-phytoene synthase
2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate
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: a part of multi-step reaction (see R07916, R02065+R07270) subsequently R07270 a part of multi-step reaction (see R10177, R02065+R04218) a part of multi-step reaction (see R12281, R02065+R12280)
natural substrates
geranylfarnesyl diphosphate synthase
geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate
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natural substrates
trifunctional (all-E)-isoprenyl diphospate synthase
geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate
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natural substrates
alcohol dehydrogenase
geraniol + NAD+ = geranial + NADH + H+
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: NADP+ (ec 1.1.1.183, see R03581)
natural substrates
geraniol dehydrogenase (NAD+)
geraniol + NAD+ = geranial + NADH + H+
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: NADP+ (ec 1.1.1.183, see R03581)
natural substrates
aryl-alcohol dehydrogenase
geraniol + NAD+ = geranial + NADH + H+
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: NADP+ (ec 1.1.1.183, see R03581)
natural substrates
ophiobolin F synthase
(2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O = ophiobolin F + diphosphate
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natural substrates