2-methylfumaryl-CoA hydratase
Pathways
ethylmalonyl-CoA pathway (BRENDA)
:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
(S)-citramalyl-CoA = 3-methylfumaryl-CoA + H2O
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natural substrates
3-methylfumaryl-CoA hydratase
(S)-citramalyl-CoA = 3-methylfumaryl-CoA + H2O
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natural substrates
2-methylfumaryl-CoA isomerase
2-methylfumaryl-CoA = 3-methylfumaryl-CoA
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natural substrates
crotonyl-CoA carboxylase/reductase
(2S)-ethylmalonyl-CoA + NADP+ = (E)-but-2-enoyl-CoA + CO2 + NADPH + H+
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: crotonyl-CoA carboxylase/reductase
natural substrates
ethylmalonyl-CoA mutase
(2R)-ethylmalonyl-CoA = (2S)-methylsuccinyl-CoA
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: (2R)-ethylmalonyl-CoA mutase
natural substrates
(2S)-methylsuccinyl-CoA dehydrogenase
(2S)-methylsuccinyl-CoA + electron-transfer flavoprotein = 2-methylfumaryl-CoA + reduced electron-transfer flavoprotein
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natural substrates, protein
methylmalonyl-CoA epimerase
(2S)-ethylmalonyl-CoA = (2R)-ethylmalonyl-CoA
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natural substrates
2-methylfumaryl-CoA hydratase
(2R,3S)-2-methylmalyl-CoA = 2-methylfumaryl-CoA + H2O
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natural substrates
3-methylfumaryl-CoA hydratase
(2R,3S)-2-methylmalyl-CoA = 2-methylfumaryl-CoA + H2O
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natural substrates
malyl-CoA lyase
(2R,3S)-2-methylmalyl-CoA = propanoyl-CoA + glyoxylate
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natural substrates
malyl-CoA lyase
(S)-malyl-CoA = acetyl-CoA + glyoxylate
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natural substrates
succinate-CoA ligase (ADP-forming)
ATP + malate + CoA = ADP + phosphate + malyl-CoA
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: reversible
natural substrates
malate-CoA ligase
ATP + malate + CoA = ADP + phosphate + malyl-CoA
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: reversible
natural substrates