Pathways
3-phenylpropionate degradation (BRENDA)
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:= BRENDA, 
:= KEGG, 
:= MetaCyc, 
:= SABIO-RK
:= amino acid sequences 
:= show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
3-hydroxybenzoyl-CoA + H2O = CoA + 3-hydroxybenzoate
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natural substrates
acyl-CoA hydrolase
3-hydroxybenzoyl-CoA + H2O = CoA + 3-hydroxybenzoate
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natural substrates
4-hydroxybenzoyl-CoA thioesterase
3-hydroxybenzoyl-CoA + H2O = CoA + 3-hydroxybenzoate
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natural substrates
3-hydroxybenzoate 6-monooxygenase
3-hydroxybenzoate + NADPH + O2 = 2,5-dihydroxybenzoate + NADP+ + H2O
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natural substrates
benzoyl-CoA 3-monooxygenase
benzoyl-CoA + NADPH + H+ + O2 = 3-hydroxybenzoyl-CoA + NADP+ + H2O
; "show the reaction diagram")
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natural substrates
3-phenylpropionyl-CoA + acceptor = cinnamoyl-CoA + reduced acceptor
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: The reaction proceeds without added cofactor. The enzyme uses FAD. [10086844]natural substrates, generic
3-phenylpropionyl-CoA dehydrogenase
3-phenylpropionyl-CoA + acceptor = cinnamoyl-CoA + reduced acceptor
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: The reaction proceeds without added cofactor. The enzyme uses FAD. [10086844]natural substrates, generic
3-phenylpropionic acid-CoA ligase
3-phenylpropanoate + CoA + ATP = 3-phenylpropionyl-CoA + AMP + diphosphate
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natural substrates
3-phenylpropanoate + CoA + ATP = 3-phenylpropionyl-CoA + AMP + diphosphate
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natural substrates
acetaldehyde dehydrogenase (acetylating)
acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+
: aerobic toluene degradation,3-phenylpropionate degradation,
threonine metabolism,
ethanol fermentation
: Phenylalanine metabolism,Benzoate degradation,
Pyruvate metabolism,
Dioxin degradation,
Xylene degradation,
Metabolic pathways,
Microbial metabolism in diverse environments,
Degradation of aromatic compounds
: 2-hydroxypenta-2,4-dienoate degradation,sulfoacetaldehyde degradation IV,
2-deoxy-D-ribose degradation I,
L-threonine degradation IV,
ethanolamine utilization,
heterolactic fermentation,
triethylamine degradation,
2-deoxy-alpha-D-ribose 1-phosphate degradation,
superpathway of fermentation (Chlamydomonas reinhardtii),
pyruvate fermentation to ethanol III,
mixed acid fermentation,
acetylene degradation (anaerobic),
pyruvate fermentation to ethanol I,
2-aminoethylphosphonate degradation I,
ethanol degradation I
; "show the reaction diagram")
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natural substrates
hexadecanal dehydrogenase (acylating)
acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+
: aerobic toluene degradation,3-phenylpropionate degradation,
threonine metabolism,
ethanol fermentation
: Phenylalanine metabolism,Benzoate degradation,
Pyruvate metabolism,
Dioxin degradation,
Xylene degradation,
Metabolic pathways,
Microbial metabolism in diverse environments,
Degradation of aromatic compounds
: 2-hydroxypenta-2,4-dienoate degradation,sulfoacetaldehyde degradation IV,
2-deoxy-D-ribose degradation I,
L-threonine degradation IV,
ethanolamine utilization,
heterolactic fermentation,
triethylamine degradation,
2-deoxy-alpha-D-ribose 1-phosphate degradation,
superpathway of fermentation (Chlamydomonas reinhardtii),
pyruvate fermentation to ethanol III,
mixed acid fermentation,
acetylene degradation (anaerobic),
pyruvate fermentation to ethanol I,
2-aminoethylphosphonate degradation I,
ethanol degradation I
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natural substrates
butanal dehydrogenase
acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+
: aerobic toluene degradation,3-phenylpropionate degradation,
threonine metabolism,
ethanol fermentation
: Phenylalanine metabolism,Benzoate degradation,
Pyruvate metabolism,
Dioxin degradation,
Xylene degradation,
Metabolic pathways,
Microbial metabolism in diverse environments,
Degradation of aromatic compounds
: 2-hydroxypenta-2,4-dienoate degradation,sulfoacetaldehyde degradation IV,
2-deoxy-D-ribose degradation I,
L-threonine degradation IV,
ethanolamine utilization,
heterolactic fermentation,
triethylamine degradation,
2-deoxy-alpha-D-ribose 1-phosphate degradation,
superpathway of fermentation (Chlamydomonas reinhardtii),
pyruvate fermentation to ethanol III,
mixed acid fermentation,
acetylene degradation (anaerobic),
pyruvate fermentation to ethanol I,
2-aminoethylphosphonate degradation I,
ethanol degradation I
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natural substrates
propanal dehydrogenase (CoA-propanoylating)
acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+
: aerobic toluene degradation,3-phenylpropionate degradation,
threonine metabolism,
ethanol fermentation
: Phenylalanine metabolism,Benzoate degradation,
Pyruvate metabolism,
Dioxin degradation,
Xylene degradation,
Metabolic pathways,
Microbial metabolism in diverse environments,
Degradation of aromatic compounds
: 2-hydroxypenta-2,4-dienoate degradation,sulfoacetaldehyde degradation IV,
2-deoxy-D-ribose degradation I,
L-threonine degradation IV,
ethanolamine utilization,
heterolactic fermentation,
triethylamine degradation,
2-deoxy-alpha-D-ribose 1-phosphate degradation,
superpathway of fermentation (Chlamydomonas reinhardtii),
pyruvate fermentation to ethanol III,
mixed acid fermentation,
acetylene degradation (anaerobic),
pyruvate fermentation to ethanol I,
2-aminoethylphosphonate degradation I,
ethanol degradation I
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natural substrates
4-hydroxy-2-oxoheptanedioate aldolase
4-hydroxy-2-oxovalerate = pyruvate + acetaldehyde
; "show the reaction diagram")
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natural substrates
4-hydroxy-4-methyl-2-oxoglutarate aldolase
4-hydroxy-2-oxovalerate = pyruvate + acetaldehyde
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natural substrates
4-hydroxy-2-oxovalerate aldolase
4-hydroxy-2-oxovalerate = pyruvate + acetaldehyde
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natural substrates
4-hydroxy-2-oxohexanoate aldolase
4-hydroxy-2-oxovalerate = pyruvate + acetaldehyde
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natural substrates
2-oxopent-4-enoate hydratase
(S)-4-hydroxy-2-oxopentanoate = (2Z)-2-hydroxypenta-2,4-dienoate + H2O
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natural substrates
3-(3-hydroxyphenyl)propanoate hydroxylase
3-(3-hydroxyphenyl)propanoate + NADH + H+ + O2 = 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD+
; "show the reaction diagram")
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natural substrates
3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase
3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+ = 3-(2,3-dihydroxyphenyl)propanoate + NADH + H+
; "show the reaction diagram")
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natural substrates
3-phenylpropanoate dioxygenase
3-phenylpropanoate + NADH + H+ + O2 = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+
; "show the reaction diagram")
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: HcaA1 HcaA2 HcaC HcaDnatural substrates
3-carboxyethylcatechol 2,3-dioxygenase
3-(2,3-dihydroxyphenyl)propanoate + O2 = (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate
; "show the reaction diagram")
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natural substrates
2-hydroxy-6-oxonona-2,4-dienedioate hydrolase
(2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O = (2Z)-2-hydroxypenta-2,4-dienoate + succinate
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natural substrates
gentisate 1,2-dioxygenase
2,5-dihydroxybenzoate + O2 = maleylpyruvate
; "show the reaction diagram")
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natural substrates
5-aminosalicylate 1,2-dioxygenase
2,5-dihydroxybenzoate + O2 = maleylpyruvate
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natural substrates
maleylacetoacetate isomerase
3-Maleylpyruvate = 3-fumarylpyruvate
; "show the reaction diagram")
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natural substrates
maleylpyruvate isomerase
3-Maleylpyruvate = 3-fumarylpyruvate
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natural substrates
3-fumarylpyruvate + H2O = fumarate + pyruvate
; "show the reaction diagram")
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natural substrates
3-fumarylpyruvate hydrolase
3-fumarylpyruvate + H2O = fumarate + pyruvate
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natural substrates
acylpyruvate hydrolase
3-fumarylpyruvate + H2O = fumarate + pyruvate
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natural substrates
oxaloacetate decarboxylase
3-fumarylpyruvate + H2O = fumarate + pyruvate
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natural substrates