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BKMS-react is an integrated and non-redundant biochemical reaction database containing known enzyme-catalyzed and spontaneous reactions. Biochemical reactions collected from BRENDA, KEGG, MetaCyc and SABIO-RK were matched and integrated by aligning substrates and products.
 

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
Please click here for detailed information about the synonyms.
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  • EC Number
  • Reaction
  • Pathways
  • Reaction IDs
  • Stoichiometry Check
  • Missing Substrate
  • Missing Product
  • Commentary
  • Remark
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check  
Commentary
O-carbamoyladenylate + tobramycin = AMP + nebramycin 5'
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nebramycin 5' synthase
O-carbamoyladenylate + tobramycin = AMP + nebramycin 5'
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nebramycin 5' synthase
tobramycin + carbamoyl phosphate + ATP + H2O = nebramycin 5' + AMP + diphosphate + phosphate
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aminoglycoside 2''-phosphotransferase
GTP + tobramycin = GDP + tobramycin 2''-phosphate
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gentamicin 2'-N-acetyltransferase
acetyl-CoA + tobramycin = CoA + N2'-acetyltobramycin
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gentamicin 3-N-acetyltransferase
acetyl-CoA + tobramycin = CoA + N2'-acetyltobramycin
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gentamicin 3-N-acetyltransferase
acetyl-CoA + tobramycin = CoA + N3'-acetyltobramycin
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aminoglycoside 3-N-acetyltransferase
acetyl-CoA + tobramycin = CoA + N3'-acetyltobramycin
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acetyl-CoA + tobramycin = CoA + N6'-acetyltobramycin
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aminoglycoside 6'-N-acetyltransferase
acetyl-CoA + tobramycin = CoA + N6'-acetyltobramycin
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gentamicin 2''-nucleotidyltransferase
dATP + tobramycin = diphosphate + 2''-deoxyadenylyltobramycin
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gentamicin 2''-nucleotidyltransferase
dTTP + tobramycin = diphosphate + 2''-deoxythymidylyltobramycin
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gentamicin 2''-nucleotidyltransferase
dCTP + tobramycin = diphosphate + 2''-deoxycytosylyltobramycin
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gentamicin 2''-nucleotidyltransferase
dGTP + tobramycin = diphosphate + 2''-deoxyguanosylyltobramycin
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aminoglycoside 6'-N-acetyltransferase
butyryl-CoA + tobramycin = CoA + N6'-butyryltobramycin
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aminoglycoside 6'-N-acetyltransferase
acetyl-CoA + nebramycin factor 6 = CoA + N6'-acetylnebramycin factor 6
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aminoglycoside 6'-N-acetyltransferase
propionyl-CoA + tobramycin = CoA + N6'-propionyltobramycin
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aminoglycoside 3-N-acetyltransferase
N-propionyl-CoA + tobramycin = CoA + N3'-propionyl-tobramycin
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gentamicin 2''-nucleotidyltransferase
GTP + tobramycin = diphosphate + 2''-guanosylyltobramycin
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gentamicin 2''-nucleotidyltransferase
CTP + tobramycin = diphosphate + 2''-cytosylyltobramycin
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gentamicin 2'-N-acetyltransferase
N-acetyl-D-glucosamine + tobramycin = D-glucosamine + N2'-acetyltobramycin
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aminoglycoside 2''-phosphotransferase
UTP + tobramycin = UDP + tobramycin 2''-phosphate
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gentamicin 2''-nucleotidyltransferase
ATP + tobramycin = diphosphate + 2''-adenylyltobramycin
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aminoglycoside 6'-N-acetyltransferase
malonyl-CoA + tobramycin = CoA + N6'-malonyltobramycin
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gentamicin 2''-nucleotidyltransferase
adenosine 5'-mono-O-phosphorothiolate + tobramycin = diphosphate + 2''-(adenosine-5'-thiophosphoryl)-tobramycin
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incomplete
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7.6.2.2
ABC-type xenobiotic transporter
tobramycin/in + ATP + H2O = tobramycin/out + ADP + phosphate
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aminoglycoside 2''-phosphotransferase
ATP + tobramycin = ADP + tobramycin 2''-phosphate
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