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BKMS-react is an integrated and non-redundant biochemical reaction database containing known enzyme-catalyzed and spontaneous reactions. Biochemical reactions collected from BRENDA, KEGG, MetaCyc and SABIO-RK were matched and integrated by aligning substrates and products.
 

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
Please click here for detailed information about the synonyms.
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  • EC Number
  • Reaction
  • Pathways
  • Reaction IDs
  • Stoichiometry Check
  • Missing Substrate
  • Missing Product
  • Commentary
  • Remark
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check  
Commentary
1,3,7-trimethylxanthine + O2 + NADPH + H+ = 1,3-dimethylxanthine + formaldehyde + NADP+ + H2O
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: caffeine demethylase
1,3,7-trimethylxanthine + O2 + NADPH + H+ = 1,3-dimethylxanthine + formaldehyde + NADP+ + H2O
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: caffeine demethylase
7-methylxanthine demethylase
1,3,7-trimethylxanthine + O2 + NADPH + H+ = 1,3-dimethylxanthine + formaldehyde + NADP+ + H2O
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: caffeine demethylase
methylxanthine N3-demethylase
Theophylline + NADPH + H+ + Oxygen <=> 1-Methylxanthine + NADP+ + Formaldehyde + H2O
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Xanthine + 2 S-Adenosyl-L-methionine <=> Theophylline + 2 S-Adenosyl-L-homocysteine
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: multi-step reaction possibly intermediate ([CPD:C16357] or [CPD:C16358])
theophylline = 1,3-dimethylurate
incomplete
: The complete reaction equation is not known.
xanthine oxidase
1,3-dimethylxanthine + H2O + O2 = 1,3-dimethylurate + H2O2
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theobromine synthase
S-adenosyl-L-methionine + 3-methylxanthine = S-adenosyl-L-homocysteine + 1,3-dimethylxanthine
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caffeine synthase
S-adenosyl-L-methionine + 3-methylxanthine = S-adenosyl-L-homocysteine + 1,3-dimethylxanthine
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theobromine synthase
S-adenosyl-L-methionine + 1-methylxanthine = S-adenosyl-L-homocysteine + 1,3-dimethylxanthine
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caffeine synthase
S-adenosyl-L-methionine + 1-methylxanthine = S-adenosyl-L-homocysteine + 1,3-dimethylxanthine
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nucleoside deoxyribosyltransferase
thymidine + theophylline = thymine + 2'-deoxytheophylline riboside
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7-methylxanthine demethylase
theophylline + 2 O2 + 2 NADH + 2 H+ = xanthine + 2 NAD+ + 2 H2O + 2 formaldehyde
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