New release (2023.1) online!
Learn more about features, functions and data:
BKMS-react is an integrated and non-redundant biochemical reaction database containing known enzyme-catalyzed and spontaneous reactions. Biochemical reactions collected from BRENDA, KEGG, MetaCyc and SABIO-RK were matched and integrated by aligning substrates and products.
 
:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
Please click here for detailed information about the synonyms.
Results per page 
  • 10 results
  • 50 results
  • 100 results
  • 500 results
  • 100000 results
Show or hide columns 
  • EC Number
  • Reaction
  • Pathways
  • Reaction IDs
  • Stoichiometry Check
  • Missing Substrate
  • Missing Product
  • Commentary
  • Remark
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check  
Commentary
progesterone monooxygenase
progesterone + reduced acceptor + O2 = testosterone acetate + acceptor + H2O
-
: BR40382show the reaction diagram
: R02212show the reaction diagram
: PROGESTERONE-MONOOXYGENASE-RXNshow the reaction diagram
-
-
progesterone 11alpha-monooxygenase
progesterone + reduced acceptor + O2 = 11alpha-hydroxyprogesterone + acceptor + H2O
: Steroid hormone biosynthesis
: BR40393show the reaction diagram, BS415731show the reaction diagram
: R02214show the reaction diagram
: PROGESTERONE-11-ALPHA-MONOOXYGENASE-RXNshow the reaction diagram
-
-
ketosteroid monooxygenase
progesterone + NADPH + H+ + O2 = testosterone acetate + NADP+ + H2O
-
: BR49815show the reaction diagram
: R02210show the reaction diagram
: RXN-7817show the reaction diagram
: 2182
-
-
steroid DELTA-isomerase
5-Pregnene-3,20-dione = 4-Pregnene-3,20-dione
: androgen and estrogen metabolism
: backdoor pathway of androgen biosynthesis,
progesterone biosynthesis
: BS1077show the reaction diagram
: RXN66-354show the reaction diagram
-
-
20alpha-hydroxysteroid dehydrogenase
progesterone + NADPH = 20alpha-hydroxyprogesterone + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276show the reaction diagram, BS188322show the reaction diagram, BS258423show the reaction diagram
: R02209show the reaction diagram
: RXN-21985show the reaction diagram
: 2181
-
: NAD+ (see R02207)
prostaglandin-E2 9-reductase
progesterone + NADPH = 20alpha-hydroxyprogesterone + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276show the reaction diagram, BS188322show the reaction diagram, BS258423show the reaction diagram
: R02209show the reaction diagram
: RXN-21985show the reaction diagram
: 2181
-
: NAD+ (see R02207)
3beta(or 20alpha)-hydroxysteroid dehydrogenase
progesterone + NADPH = 20alpha-hydroxyprogesterone + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276show the reaction diagram, BS188322show the reaction diagram, BS258423show the reaction diagram
: R02209show the reaction diagram
: RXN-21985show the reaction diagram
: 2181
-
: NAD+ (see R02207)
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
progesterone + NADPH = 20alpha-hydroxyprogesterone + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276show the reaction diagram, BS188322show the reaction diagram, BS258423show the reaction diagram
: R02209show the reaction diagram
: RXN-21985show the reaction diagram
: 2181
-
: NAD+ (see R02207)
3beta-hydroxysteroid 3-dehydrogenase
progesterone + NADPH = 20alpha-hydroxyprogesterone + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276show the reaction diagram, BS188322show the reaction diagram, BS258423show the reaction diagram
: R02209show the reaction diagram
: RXN-21985show the reaction diagram
: 2181
-
: NAD+ (see R02207)
3alpha-hydroxysteroid 3-dehydrogenase
progesterone + NADPH = 20alpha-hydroxyprogesterone + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276show the reaction diagram, BS188322show the reaction diagram, BS258423show the reaction diagram
: R02209show the reaction diagram
: RXN-21985show the reaction diagram
: 2181
-
: NAD+ (see R02207)
3(or 17)beta-hydroxysteroid dehydrogenase
progesterone + NADPH = 20alpha-hydroxyprogesterone + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276show the reaction diagram, BS188322show the reaction diagram, BS258423show the reaction diagram
: R02209show the reaction diagram
: RXN-21985show the reaction diagram
: 2181
-
: NAD+ (see R02207)
3alpha(or 20beta)-hydroxysteroid dehydrogenase
progesterone + NADPH = 20alpha-hydroxyprogesterone + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276show the reaction diagram, BS188322show the reaction diagram, BS258423show the reaction diagram
: R02209show the reaction diagram
: RXN-21985show the reaction diagram
: 2181
-
: NAD+ (see R02207)
17beta-estradiol 17-dehydrogenase
progesterone + NADPH = 20alpha-hydroxyprogesterone + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276show the reaction diagram, BS188322show the reaction diagram, BS258423show the reaction diagram
: R02209show the reaction diagram
: RXN-21985show the reaction diagram
: 2181
-
: NAD+ (see R02207)
DELTA4-3-oxosteroid 5beta-reductase
progesterone + NADPH = 20alpha-hydroxyprogesterone + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276show the reaction diagram, BS188322show the reaction diagram, BS258423show the reaction diagram
: R02209show the reaction diagram
: RXN-21985show the reaction diagram
: 2181
-
: NAD+ (see R02207)
20alpha-hydroxysteroid dehydrogenase
progesterone + NADH = 20alpha-hydroxyprogesterone + NAD+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276_WOPThis reaction also exists with phosphate.show the reaction diagram, BS188322_WOPThis reaction also exists with phosphate.show the reaction diagram
: R02207show the reaction diagram
: RXN-21985_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-22017show the reaction diagram
: 2179
-
: NADP+ (see R02209)
3beta(or 20alpha)-hydroxysteroid dehydrogenase
progesterone + NADH = 20alpha-hydroxyprogesterone + NAD+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276_WOPThis reaction also exists with phosphate.show the reaction diagram, BS188322_WOPThis reaction also exists with phosphate.show the reaction diagram
: R02207show the reaction diagram
: RXN-21985_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-22017show the reaction diagram
: 2179
-
: NADP+ (see R02209)
3alpha-hydroxysteroid 3-dehydrogenase
progesterone + NADH = 20alpha-hydroxyprogesterone + NAD+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276_WOPThis reaction also exists with phosphate.show the reaction diagram, BS188322_WOPThis reaction also exists with phosphate.show the reaction diagram
: R02207show the reaction diagram
: RXN-21985_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-22017show the reaction diagram
: 2179
-
: NADP+ (see R02209)
3(or 17)beta-hydroxysteroid dehydrogenase
progesterone + NADH = 20alpha-hydroxyprogesterone + NAD+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276_WOPThis reaction also exists with phosphate.show the reaction diagram, BS188322_WOPThis reaction also exists with phosphate.show the reaction diagram
: R02207show the reaction diagram
: RXN-21985_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-22017show the reaction diagram
: 2179
-
: NADP+ (see R02209)
3alpha(or 20beta)-hydroxysteroid dehydrogenase
progesterone + NADH = 20alpha-hydroxyprogesterone + NAD+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276_WOPThis reaction also exists with phosphate.show the reaction diagram, BS188322_WOPThis reaction also exists with phosphate.show the reaction diagram
: R02207show the reaction diagram
: RXN-21985_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-22017show the reaction diagram
: 2179
-
: NADP+ (see R02209)
17beta-estradiol 17-dehydrogenase
progesterone + NADH = 20alpha-hydroxyprogesterone + NAD+
: Steroid hormone biosynthesis,
Metabolic pathways
: BS187276_WOPThis reaction also exists with phosphate.show the reaction diagram, BS188322_WOPThis reaction also exists with phosphate.show the reaction diagram
: R02207show the reaction diagram
: RXN-21985_WOPThis reaction also exists with phosphate.show the reaction diagram, RXN-22017show the reaction diagram
: 2179
-
: NADP+ (see R02209)
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
progesterone + NADPH + H+ = 5alpha-pregnan-3-20-dione + NADP+
: Steroid hormone biosynthesis
: digitoxigenin biosynthesis,
allopregnanolone biosynthesis
: BS258427show the reaction diagram
: R02208show the reaction diagram
: PROGESTERONE-5-ALPHA-REDUCTASE-RXNshow the reaction diagram
: 2180
-
-
3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)
progesterone + NADPH + H+ = 5alpha-pregnan-3-20-dione + NADP+
: Steroid hormone biosynthesis
: digitoxigenin biosynthesis,
allopregnanolone biosynthesis
: BS258427show the reaction diagram
: R02208show the reaction diagram
: PROGESTERONE-5-ALPHA-REDUCTASE-RXNshow the reaction diagram
: 2180
-
-
steroid DELTA-isomerase
pregnenolone + NAD+ = progesterone + NADH + H+
: androgen and estrogen metabolism
: Steroid hormone biosynthesis,
Metabolic pathways
: BS383305show the reaction diagram
: R02216show the reaction diagram
: RXN-9722show the reaction diagram
: 2188
-
: 3beta-hydroxysteroid dehydrogenase/ Delta5-Delta4-isomerase two-step reaction
pregnenolone + NAD+ = progesterone + NADH + H+
: androgen and estrogen metabolism
: Steroid hormone biosynthesis,
Metabolic pathways
: BS383305show the reaction diagram
: R02216show the reaction diagram
: RXN-9722show the reaction diagram
: 2188
-
: 3beta-hydroxysteroid dehydrogenase/ Delta5-Delta4-isomerase two-step reaction
3beta-hydroxy-DELTA5-steroid dehydrogenase
pregnenolone + NAD+ = progesterone + NADH + H+
: androgen and estrogen metabolism
: Steroid hormone biosynthesis,
Metabolic pathways
: BS383305show the reaction diagram
: R02216show the reaction diagram
: RXN-9722show the reaction diagram
: 2188
-
: 3beta-hydroxysteroid dehydrogenase/ Delta5-Delta4-isomerase two-step reaction
3(or 17)beta-hydroxysteroid dehydrogenase
pregnenolone + NAD+ = progesterone + NADH + H+
: androgen and estrogen metabolism
: Steroid hormone biosynthesis,
Metabolic pathways
: BS383305show the reaction diagram
: R02216show the reaction diagram
: RXN-9722show the reaction diagram
: 2188
-
: 3beta-hydroxysteroid dehydrogenase/ Delta5-Delta4-isomerase two-step reaction
DELTA4-3-oxosteroid 5beta-reductase
progesterone + NADPH + H+ = 5beta-pregnane-3,20-dione + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: digitoxigenin biosynthesis
: BS389592show the reaction diagram
: R02219show the reaction diagram
: RXN-9726show the reaction diagram
: 2191
-
-
1.3.1.M16
progesterone + NADPH + H+ = 5beta-pregnane-3,20-dione + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: digitoxigenin biosynthesis
: BS389592show the reaction diagram
: R02219show the reaction diagram
: RXN-9726show the reaction diagram
: 2191
-
-
3-oxo-5beta-steroid 4-dehydrogenase
progesterone + NADPH + H+ = 5beta-pregnane-3,20-dione + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: digitoxigenin biosynthesis
: BS389592show the reaction diagram
: R02219show the reaction diagram
: RXN-9726show the reaction diagram
: 2191
-
-
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
progesterone + NADPH + H+ = 5beta-pregnane-3,20-dione + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: digitoxigenin biosynthesis
: BS389592show the reaction diagram
: R02219show the reaction diagram
: RXN-9726show the reaction diagram
: 2191
-
-
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
progesterone + NADPH + H+ = 5beta-pregnane-3,20-dione + NADP+
: Steroid hormone biosynthesis,
Metabolic pathways
: digitoxigenin biosynthesis
: BS389592show the reaction diagram
: R02219show the reaction diagram
: RXN-9726show the reaction diagram
: 2191
-
-
steroid 17alpha-monooxygenase
progesterone + [reduced NADPH-hemoprotein reductase] + O2 = 17alpha-hydroxyprogesterone + [oxidized NADPH-hemoprotein reductase] + H2O
: androgen and estrogen metabolism
: Steroid hormone biosynthesis,
Metabolic pathways
: BS258003show the reaction diagram
: R02211show the reaction diagram
-
-
17alpha-hydroxyprogesterone deacetylase
progesterone + [reduced NADPH-hemoprotein reductase] + O2 = 17alpha-hydroxyprogesterone + [oxidized NADPH-hemoprotein reductase] + H2O
: androgen and estrogen metabolism
: Steroid hormone biosynthesis,
Metabolic pathways
: BS258003show the reaction diagram
: R02211show the reaction diagram
-
-
steroid 21-monooxygenase
progesterone + [reduced NADPH-hemoprotein reductase] + O2 = 11-deoxycorticosterone + [oxidized NADPH-hemoprotein reductase] + H2O
: androgen and estrogen metabolism
: Steroid hormone biosynthesis,
Metabolic pathways
: BS427511show the reaction diagram
: R02213show the reaction diagram
-
-
steroid 15beta-monooxygenase
Progesterone + 2 Reduced [2Fe-2S] ferredoxin + Oxygen <=> 15beta-Hydroxyprogesterone + 2 Oxidized [2Fe-2S] ferredoxin + H2O
-
: R09587show the reaction diagram
: RXN-11240show the reaction diagram
generic compounds
-
unspecific monooxygenase
progesterone + NADPH + O2 = deoxycorticosterone + NADP+ + H2O
-
: BS186802show the reaction diagram
: 7228
-
-
steroid 21-monooxygenase
progesterone + NADPH + O2 = deoxycorticosterone + NADP+ + H2O
-
: BS186802show the reaction diagram
: 7228
-
-
3-oxosteroid 1-dehydrogenase
progesterone + 2,6-dichlorophenol-indophenol = pregna-1,4-diene-3,20-dione + reduced 2,6-dichlorophenol-indophenol
-
: BS398163show the reaction diagram
: 16039
-
-
3-oxo-5beta-steroid 4-dehydrogenase
5beta-Pregnane-3,20-dione + Acceptor <=> Progesterone + Reduced acceptor
: Steroid hormone biosynthesis,
Metabolic pathways
: R02215show the reaction diagram
generic compounds
-
steroid 11beta-monooxygenase
Progesterone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> 11beta-Hydroxyprogesterone + 2 Oxidized ferredoxin + H2O
: Steroid hormone biosynthesis
: R02218show the reaction diagram
n.a.
-
steroid 17alpha-monooxygenase
progesterone + dioxygen + reduced [NADPH-hemoprotein reductase] = 17-alpha-hydroxyprogesterone + oxidized [NADPH-hemoprotein reductase] + H2O
: backdoor pathway of androgen biosynthesis,
glucocorticoid biosynthesis
: RXN66-355show the reaction diagram
generic compounds
-
steroid 21-monooxygenase
progesterone + reduced [NADPH-hemoprotein reductase] + dioxygen = 11-deoxycorticosterone + oxidized [NADPH-hemoprotein reductase] + H2O
: mineralocorticoid biosynthesis
: RXN66-358show the reaction diagram
generic compounds
-
steroid 21-monooxygenase
progesterone + [reduced NADPH-P450 reductase] + O2 = 11-deoxycorticosterone + [oxidized NADPH-P450 reductase] + H2O
-
: BS427514show the reaction diagram
generic compounds
-
steroid 21-monooxygenase
progesterone + [reduced NADPH-hemoprotein reductase] + O2 = 16alpha-hydroxy-progesterone + [oxidized NADPH-hemoprotein reductase] + H2O
-
: BS428887show the reaction diagram
-
-
steroid 17alpha-monooxygenase
progesterone + [reduced NADPH-hemoprotein reductase] + O2 = 16alpha-hydroxy-progesterone + [oxidized NADPH-hemoprotein reductase] + H2O
-
: BS428887show the reaction diagram
-
-
17alpha-hydroxyprogesterone deacetylase
progesterone + [reduced NADPH-hemoprotein reductase] + O2 = 16alpha-hydroxy-progesterone + [oxidized NADPH-hemoprotein reductase] + H2O
-
: BS428887show the reaction diagram
-
-
steroid 17alpha-monooxygenase
progesterone + [reduced NADPH-hemoprotein reductase] + O2 = 17alpha-hydroxyprogesterone + 16alpha-hydroxyprogesterone + [oxidized NADPH-hemoprotein reductase] + H2O
-
: BS427512show the reaction diagram
-
-
3-oxo-5beta-steroid 4-dehydrogenase
5beta-pregnan-3,20-dione + menaphthone = 4-pregnen-3,20-dione + reduced menaphthone
-
: BS258883show the reaction diagram
-
-
3-oxo-5beta-steroid 4-dehydrogenase
5beta-pregnan-3,20-dione + phenazine methosulfate = 4-pregnen-3,20-dione + reduced menazine methosulfate
-
: BS258884show the reaction diagram
-
-
steroid 15beta-monooxygenase
progesterone + reduced ferredoxin + O2 + H+ = 15beta-hydroxyprogesterone + oxidized ferredoxin + H2O
-
: BR49149show the reaction diagram
-
-
steroid 15beta-monooxygenase
progesterone + reduced adrenodoxin + O2 = 15beta-hydroxy-progesterone + oxidized adrenodoxin + H2O
-
: BS406466show the reaction diagram
generic compounds
-
steroid 11beta-monooxygenase
progesterone + reduced adrenodoxin + O2 = 11beta-hydroxyprogesterone + oxidized adrenodoxin + H2O
-
: BS426947show the reaction diagram
generic compounds
-
steroid 15beta-monooxygenase
progesterone + reduced adrenodoxin + O2 = 15beta-hydroxy-progesterone + 11alpha-hydroxy-progesterone + oxidized adrenodoxin + H2O
-
: BS443861show the reaction diagram
generic compounds
-
steroid 15beta-monooxygenase
progesterone + reduced megaredoxin + O2 = 15beta-hydroxyprogesterone + oxidized megaredoxin + H2O
-
: BS406469show the reaction diagram
generic compounds
-
steroid 21-monooxygenase
progesterone + AH2 + O2 = deoxycorticosterone + A + H2O
-
: BS406463show the reaction diagram
-
-
steroid 17alpha-monooxygenase
2 progesterone + 2 AH2 + 2 O2 = 17alpha-hydroxyprogesterone + 16alpha-hydroxyprogesterone + 2 A + 2 H2O
-
: BS394960show the reaction diagram
-
-
steroid 17alpha-monooxygenase
progesterone + AH2 + O2 = 17alpha-hydroxyprogesterone + A + H2O
-
: BS394961show the reaction diagram
-
-
17alpha-hydroxyprogesterone deacetylase
progesterone + AH2 + O2 = 17alpha-hydroxyprogesterone + A + H2O
-
: BS394961show the reaction diagram
-
-
steroid 9alpha-monooxygenase
progesterone + AH2 + O2 = 9alpha-hydroxyprogesterone + A + H2O
-
: BS394962show the reaction diagram
-
-
steroid 21-monooxygenase
progesterone + NADH + O2 = deoxycorticosterone + NAD+ + H2O
-
: BS186795show the reaction diagram
-
-
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
4-pregnen-3alpha-ol-2-one + NAD+ = 4-pregnen-3,20-dione + NADH + H+
-
: BS438872show the reaction diagram
-
-
3-oxo-5beta-steroid 4-dehydrogenase
4-pregnen-3,20-dione + NADH = 5beta-pregnan-3,20-dione + NAD+
-
: BS258873show the reaction diagram
-
-
20alpha-hydroxysteroid dehydrogenase
20alpha-hydroxyprogesterone + NADH + H+ = progesterone + NAD+
-
: BS424504_WOPThis reaction also exists with phosphate.show the reaction diagram
-
-
3alpha-hydroxysteroid 3-dehydrogenase
20alpha-hydroxyprogesterone + NADH + H+ = progesterone + NAD+
-
: BS424504_WOPThis reaction also exists with phosphate.show the reaction diagram
-
-
3beta-hydroxysteroid 3-dehydrogenase
pregnenolone + NADH + H+ = progesterone + NAD+
-
: BS426945show the reaction diagram
-
-
3beta-hydroxy-DELTA5-steroid dehydrogenase
pregnenolone + NAD+ = isoprogesterone + progesterone + NADH + H+
-
: BS398144show the reaction diagram
incomplete
-
indanol dehydrogenase
progesterone + NADH = 3alpha-hydroxy-4-pregnen-20-one + NAD+
-
: BS187028_WOPThis reaction also exists with phosphate.show the reaction diagram
-
-
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
progesterone + NADH = 3alpha-hydroxy-4-pregnen-20-one + NAD+
-
: BS187028_WOPThis reaction also exists with phosphate.show the reaction diagram
-
-
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
progesterone + NADH = 3alpha-hydroxy-4-pregnen-20-one + NAD+
-
: BS187028_WOPThis reaction also exists with phosphate.show the reaction diagram
-
-
3beta-hydroxy-DELTA5-steroid dehydrogenase
5-pregnen-3beta-ol-2-one + NAD+ = progesterone + NADH
-
: BS370818show the reaction diagram
-
-
20alpha-hydroxysteroid dehydrogenase
4-pregnen-20alpha-ol-3-one + NAD+ = 4-pregnen-3,20-dione + NADH + H+
-
: BS372103_WOPThis reaction also exists with phosphate.show the reaction diagram
incomplete
-
steroid DELTA-isomerase
pregnenolone = progesterone
-
: BS428886show the reaction diagram
-
-
steroid 17alpha-monooxygenase
progesterone + 2 AH2 + 2 O2 = androstenedione + acetate + 2 A + 2 H2O
-
: BS407298show the reaction diagram
-
-
3alpha(or 20beta)-hydroxysteroid dehydrogenase
progesterone + NADP+ = 20beta-hydroxy-pregn-4-ene-3-one + NADPH + H+
-
: BS437833show the reaction diagram
-
-
20alpha-hydroxysteroid dehydrogenase
20alpha-hydroxyprogesterone + NADPH + H+ = progesterone + NADP+
-
: BS424504show the reaction diagram
-
-
3alpha-hydroxysteroid 3-dehydrogenase
20alpha-hydroxyprogesterone + NADPH + H+ = progesterone + NADP+
-
: BS424504show the reaction diagram
-
-
3(or 17)beta-hydroxysteroid dehydrogenase
pregnenolone + NADPH = progesterone + NADP+
-
: BS389583show the reaction diagram
-
-
progesterone monooxygenase
progesterone + NADPH + H+ + O2 = 16alpha-hydroxyprogesterone + 2beta,16alpha-dihydroxyprogesterone + NADP+ + H2O
-
: BS287904show the reaction diagram
incomplete
-
progesterone 11alpha-monooxygenase
progesterone + NADPH + O2 = 11alpha-hydroxyprogesterone + NADP+ + H2O
-
: BS287964show the reaction diagram
-
-
3(or 17)beta-hydroxysteroid dehydrogenase
pregnenolone + NADP+ = progesterone + NADPH + H+
-
: BS406431show the reaction diagram
-
-
steroid 17alpha-monooxygenase
progesterone + 2 NADPH + 2 H+ + 2 O2 = androstenedione + acetate + 2 NADP+ + 2 H2O
-
: BS407302show the reaction diagram
-
-
3beta-hydroxy-DELTA5-steroid dehydrogenase
progesterone + NADPH = 3beta-hydroxy-4-pregnen-20-one + NADP+
-
: BS257053show the reaction diagram
-
-
3beta-hydroxysteroid 3-dehydrogenase
progesterone + NADPH = 3beta-hydroxy-4-pregnen-20-one + NADP+
-
: BS257053show the reaction diagram
-
-
indanol dehydrogenase
progesterone + NADPH = 3alpha-hydroxy-4-pregnen-20-one + NADP+
-
: BS187028show the reaction diagram
-
-
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
progesterone + NADPH = 3alpha-hydroxy-4-pregnen-20-one + NADP+
-
: BS187028show the reaction diagram
-
-
17beta-estradiol 17-dehydrogenase
progesterone + NADPH + H+ = 4-preggnen-3beta-ol-20-one + NADP+
-
: BS461323show the reaction diagram
n.a.
-
3alpha-hydroxysteroid 3-dehydrogenase
3alpha-hydroxypregn-4-en-20-one + NADP+ = pregn-4-en-3,20-dione + NADPH + H+
-
: BS370798show the reaction diagram
-
-
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
3alpha-hydroxypregn-4-en-20-one + NADP+ = pregn-4-en-3,20-dione + NADPH + H+
-
: BS370798show the reaction diagram
-
-
20alpha-hydroxysteroid dehydrogenase
4-pregnen-20alpha-ol-3-one + NADP+ = 4-pregnen-3,20-dione + NADPH + H+
-
: BS372103show the reaction diagram
incomplete
-
steroid 17alpha-monooxygenase
progesterone + reduced acceptor + O2 = 17alpha-hydroxyprogesterone + acceptor + H2O
-
: BS415732show the reaction diagram
-
-
17alpha-hydroxyprogesterone deacetylase
progesterone + reduced acceptor + O2 = 17alpha-hydroxyprogesterone + acceptor + H2O
-
: BS415732show the reaction diagram
-
-
steroid sulfotransferase
3'-phosphoadenylyl sulfate + progesterone = adenosine 3',5'-bisphosphate + progesterone sulfate
-
: BS458999show the reaction diagram
n.a.
-
3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)
progesterone + reduced acceptor = 5alpha-pregnan-3,20-dione + acceptor
-
: BS438426show the reaction diagram
-
-
3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)
progesterone + reduced acceptor = pregnane-3,20-dione + acceptor
-
: BS371125show the reaction diagram
-
-
3-oxosteroid 1-dehydrogenase
4-pregnene-3,20-dione + acceptor = 1,4-pregnene-3,20 dione + reduced acceptor
-
: BS258848show the reaction diagram
-
-
3-oxosteroid 1-dehydrogenase
pregn-4-ene-3,20-dione + acceptor = pregn-1,4-diene-3,20-dione + reduced acceptor
-
: BS461318show the reaction diagram
generic compounds
-
7.6.2.2
ABC-type xenobiotic transporter
ATP + H2O + progesterone/in = ADP + phosphate + progesterone/out
-
: BS376352show the reaction diagram
-
-
3-ketosteroid 9alpha-monooxygenase
4-pregnene-3,20-dione + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 = 9alpha-hydroxy-4-pregnene-3,20-dione + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
: BS418311show the reaction diagram
generic compounds
-
steroid 17alpha-monooxygenase
Progesterone + NADPH + O2 <=> 17alpha-Hydroxyprogesterone + NADP+ + H2O
-
: 7671
incomplete
-
cholesterol 24-hydroxylase
Progesterone + NADPH + O2 <=> 17alpha-Hydroxyprogesterone + NADP+ + H2O
-
: 7671
incomplete
-
unspecific monooxygenase
O2 + NADPH + Progesterone + H+ <=> H2O + 16alpha-Hydroxyprogesterone + NADP+
-
: 13565
incomplete
-
unspecific monooxygenase
Progesterone + NADPH + O2 + H+ <=> H2O + 6beta-Hydroxyprogesterone + NADP+
-
: 13564
incomplete
-