New release (2023.1) online!
Learn more about features, functions and data:
BKMS-react is an integrated and non-redundant biochemical reaction database containing known enzyme-catalyzed and spontaneous reactions. Biochemical reactions collected from BRENDA, KEGG, MetaCyc and SABIO-RK were matched and integrated by aligning substrates and products.
 
:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
Please click here for detailed information about the synonyms.
Results per page 
  • 10 results
  • 50 results
  • 100 results
  • 500 results
  • 100000 results
Show or hide columns 
  • EC Number
  • Reaction
  • Pathways
  • Reaction IDs
  • Stoichiometry Check
  • Missing Substrate
  • Missing Product
  • Commentary
  • Remark
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check  
Commentary
cystine reductase
2 glutathione + cystine = glutathione disulfide + 2 cysteine
: cysteine metabolism
: Glutathione metabolism,
Metabolic pathways,
Cysteine and methionine metabolism
: BR37026show the reaction diagram
: R01109show the reaction diagram, R01113show the reaction diagram
: 1.8.4.4-RXNshow the reaction diagram
-
-
glutathione-cystine transhydrogenase
2 glutathione + cystine = glutathione disulfide + 2 cysteine
: cysteine metabolism
: Glutathione metabolism,
Metabolic pathways,
Cysteine and methionine metabolism
: BR37026show the reaction diagram
: R01109show the reaction diagram, R01113show the reaction diagram
: 1.8.4.4-RXNshow the reaction diagram
-
-
adenylyl-sulfate reductase (glutathione)
2 glutathione + cystine = glutathione disulfide + 2 cysteine
: cysteine metabolism
: Glutathione metabolism,
Metabolic pathways,
Cysteine and methionine metabolism
: BR37026show the reaction diagram
: R01109show the reaction diagram, R01113show the reaction diagram
: 1.8.4.4-RXNshow the reaction diagram
-
-
cystine reductase
2 L-cysteine + NAD+ = L-cystine + NADH + H+
: cysteine metabolism
: Cysteine and methionine metabolism,
Metabolic pathways
: BR40533show the reaction diagram
: R00892show the reaction diagram
: CYSTINE-REDUCTASE-NADH-RXNshow the reaction diagram
-
-
cystathionine gamma-lyase
L-cystine + H2O = L-thiocysteine + pyruvate + NH3
: Cysteine and methionine metabolism,
Metabolic pathways
: BR51996show the reaction diagram
: R02408show the reaction diagram
: CYSTHIOCYS-RXNshow the reaction diagram
: 2346
-
-
cysteine-S-conjugate beta-lyase
L-cystine + H2O = L-thiocysteine + pyruvate + NH3
: Cysteine and methionine metabolism,
Metabolic pathways
: BR51996show the reaction diagram
: R02408show the reaction diagram
: CYSTHIOCYS-RXNshow the reaction diagram
: 2346
-
-
dimethylpropiothetin dethiomethylase
L-cystine + H2O = L-thiocysteine + pyruvate + NH3
: Cysteine and methionine metabolism,
Metabolic pathways
: BR51996show the reaction diagram
: R02408show the reaction diagram
: CYSTHIOCYS-RXNshow the reaction diagram
: 2346
-
-
L-cystine beta-lyase
L-cystine + H2O = L-thiocysteine + pyruvate + NH3
: Cysteine and methionine metabolism,
Metabolic pathways
: BR51996show the reaction diagram
: R02408show the reaction diagram
: CYSTHIOCYS-RXNshow the reaction diagram
: 2346
-
-
L-cystine beta-lyase
L-cystine = L-thiocysteine + 2-aminoprop-2-enoate
-
: BR51997show the reaction diagram
: RXN-15128show the reaction diagram
-
-
L-cystine = L-thiocysteine + 2-aminoprop-2-enoate
-
: BR51997show the reaction diagram
: RXN-15128show the reaction diagram
-
-
thioredoxin-disulfide reductase
cystine + NADPH + H+ = 2 cysteine + NADP+
-
: BS441244show the reaction diagram
: 696
-
-
cystine + NADPH + H+ = 2 cysteine + NADP+
-
: BS441244show the reaction diagram
: 696
-
-
glutathione-CoA-glutathione transhydrogenase
L-Cystine + Sulfate <=> S-Sulfo-L-cysteine + L-Cysteine
: Cysteine and methionine metabolism,
Metabolic pathways
: R02409show the reaction diagram
incomplete
: incomplete reaction
cystine = pyrrothine + H2O
-
: RXN-16657show the reaction diagram
-
-
L-glutamate + L-cystine = L-cystine + L-glutamate
-
: TRANS-RXN-211show the reaction diagram
-
-
cystine = cystine
-
: TRANS-RXN-267show the reaction diagram
-
-
L-cystine + H+ = L-cystine + H+
-
: TRANS-RXN-285show the reaction diagram
-
-
7.4.2.12
ABC-type cystine transporter
cystine + ATP + H2O = cystine + ADP + phosphate + H+
-
: TRANS-RXN-331show the reaction diagram
-
-
L-cystine = L-cystine
-
: TRANS-RXN0-507show the reaction diagram
-
-
7.4.2.12
ABC-type cystine transporter
L-cystine + ATP + H2O = L-cystine + phosphate + H+ + ADP
-
: TRANS-RXN0-593show the reaction diagram
-
-
L-amino-acid oxidase
L-cystine + H2O + O2 = 2-oxo-3-mercaptopropanoic acid + NH3 + H2O2
-
: BS363800show the reaction diagram
incomplete
-
thiol oxidase
cysteine + O2 = cystine + H2O2
-
: BS376588show the reaction diagram
incomplete
-
glutathione oxidase
cysteine + O2 = cystine + H2O2
-
: BS376588show the reaction diagram
incomplete
-
thioredoxin-disulfide reductase
L-cysteine + NADPH = L-cystine + NADP+
-
: BS260491show the reaction diagram
incomplete
-
glutathione-homocystine transhydrogenase
cysteine + homocystine = cystine + 2 homocysteine
-
: BS441243show the reaction diagram
incomplete
-
7.6.2.14
ABC-type aliphatic sulfonate transporter
ATP + H2O + cystine-[cystine-binding protein][side 1] = ADP + phosphate + cystine[side 2] + [cystine-binding protein][side 1]
-
: BS449604show the reaction diagram
n.a.
-
phosphopantothenate-cysteine ligase (CTP)
ATP + (R)-4'-phosphopantothenate + cystine = (R)-4'-phosphopantothenoyl-L-cystine + ADP + phosphate
-
: BS363668show the reaction diagram
-
-
7.4.2.12
ABC-type cystine transporter
ATP + H2O + L-cystine-[cystine-binding protein][side 1] = ADP + phosphate + L-cystine[side 2] + [cystine-binding protein][side 1]
-
: BR52764show the reaction diagram
n.a.
-
7.4.2.12
ABC-type cystine transporter
ATP + H2O + L-cystine-[cystine-binding protein II][side 1] = ADP + phosphate + L-cystine[side 2] + [cystine-binding protein II][side 1]
-
: BS447066show the reaction diagram
n.a.
-
7.4.2.12
ABC-type cystine transporter
ATP + H2O + L-cystine-[cystine-binding protein I][side 1] = ADP + phosphate + L-cystine[side 2] + [cystine-binding protein I][side 1]
-
: BS447067show the reaction diagram
n.a.
-
7.4.2.12
ABC-type cystine transporter
ATP + H2O + L-cystine-[cystine-binding protein Ngo0372](side 1) = ADP + phosphate + L-cystine(side 2) + [cystine-binding protein Ngo0372](side 1)
-
: BS447068show the reaction diagram
n.a.
-
7.4.2.12
ABC-type cystine transporter
ATP + H2O + L-cystine-[cystine-binding protein TcyA](side 1) = ADP + phosphate + L-cystine(side 2) + [cystine-binding protein TcyA](side 1)
-
: BS446161show the reaction diagram
n.a.
-
7.4.2.12
ABC-type cystine transporter
ATP + H2O + L-cystine-[cystine-binding protein](side 1) = ADP + phosphate + L-cystine(side 2) + [cystine-binding protein](side 1)
-
: BS446162show the reaction diagram
n.a.
-
cystinyl aminopeptidase
L-cystine-di-beta-naphthylamide + 2 H2O = L-cystine + 2 beta-naphthylamine
-
: BS450151show the reaction diagram
-
-
protein-disulfide reductase (glutathione)
L-cysteine + protein disulfide = cystine + protein-dithiol
-
: BS260428show the reaction diagram
-
-
cysteine desulfurase
L-cystine + Slr0077 = pyruvate + Slr0077-SSH
-
: BS379984show the reaction diagram
n.a.
-
lytic starch monooxygenase
starch + cysteine + O2 = malto-oligosaccharide aldonic acid + cystine + H2O
-
: BS439908show the reaction diagram
generic compounds
-
L-cysteinyl-L-histidinylsulfoxide synthase
L-cysteine + O2 = L-cystine
-
: BS260460show the reaction diagram
incomplete
-
glutathione oxidase
L-cysteine + O2 = L-cystine
-
: BS260460show the reaction diagram
incomplete
-
cystathionine gamma-lyase
L-cystine + 2 H2O = 2 NH3 + 2 pyruvate + 2 hydrogen sulfide
-
: BS368532show the reaction diagram
-
-
alliin lyase
L-cystine = pyruvate + NH4+ + S2- + L-cysteine
-
: BS388991show the reaction diagram
incomplete
-
5-oxoprolinase (ATP-hydrolysing)
L-2-iminothiazolidine-4-carboxylate + H2O = L-cystine
-
: BS140879show the reaction diagram
incomplete
-
gamma-glutamyltransferase
5-L-glutamyl-4-nitroanilide + L-cystine = 4-nitroaniline + 5-L-glutamyl-L-cystine
-
: BS321633show the reaction diagram
incomplete
-
bacterial leucyl aminopeptidase
L-cystinyl-p-nitroanilide + H2O = L-cystine + p-nitroaniline
-
: BS392362show the reaction diagram
incomplete
-
aminopeptidase I
Cystinyl 4-nitroanilide + H2O = Cystine + 4-nitroaniline
-
: BS14571show the reaction diagram
incomplete
-
cystinyl aminopeptidase
Cystinyl 4-nitroanilide + H2O = Cystine + 4-nitroaniline
-
: BS14571show the reaction diagram
incomplete
-
glutamine-phenylpyruvate transaminase
L-cystine + phenylpyruvate = cystine ketimine + phenylalanine
-
: BS356837show the reaction diagram
incomplete
-