homoserine O-acetyltransferase
Pathways
threonine metabolism (BRENDA)






EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
acetyl-CoA + L-homoserine = CoA + O-acetyl-L-homoserine
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natural substrates
acetaldehyde dehydrogenase (acetylating)
acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+

Benzoate degradation,
Pyruvate metabolism,
Dioxin degradation,
Xylene degradation,
Metabolic pathways,
Microbial metabolism in diverse environments,
Degradation of aromatic compounds

2-deoxy-D-ribose degradation I,
L-threonine degradation IV,
ethanolamine utilization,
heterolactic fermentation,
triethylamine degradation,
2-deoxy-alpha-D-ribose 1-phosphate degradation,
superpathway of fermentation (Chlamydomonas reinhardtii),
2-hydroxypenta-2,4-dienoate degradation,
pyruvate fermentation to ethanol III,
mixed acid fermentation,
acetylene degradation (anaerobic),
pyruvate fermentation to ethanol I,
2-aminoethylphosphonate degradation I,
ethanol degradation I
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natural substrates
hexadecanal dehydrogenase (acylating)
acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+

Benzoate degradation,
Pyruvate metabolism,
Dioxin degradation,
Xylene degradation,
Metabolic pathways,
Microbial metabolism in diverse environments,
Degradation of aromatic compounds

2-deoxy-D-ribose degradation I,
L-threonine degradation IV,
ethanolamine utilization,
heterolactic fermentation,
triethylamine degradation,
2-deoxy-alpha-D-ribose 1-phosphate degradation,
superpathway of fermentation (Chlamydomonas reinhardtii),
2-hydroxypenta-2,4-dienoate degradation,
pyruvate fermentation to ethanol III,
mixed acid fermentation,
acetylene degradation (anaerobic),
pyruvate fermentation to ethanol I,
2-aminoethylphosphonate degradation I,
ethanol degradation I
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natural substrates
butanal dehydrogenase
acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+

Benzoate degradation,
Pyruvate metabolism,
Dioxin degradation,
Xylene degradation,
Metabolic pathways,
Microbial metabolism in diverse environments,
Degradation of aromatic compounds

2-deoxy-D-ribose degradation I,
L-threonine degradation IV,
ethanolamine utilization,
heterolactic fermentation,
triethylamine degradation,
2-deoxy-alpha-D-ribose 1-phosphate degradation,
superpathway of fermentation (Chlamydomonas reinhardtii),
2-hydroxypenta-2,4-dienoate degradation,
pyruvate fermentation to ethanol III,
mixed acid fermentation,
acetylene degradation (anaerobic),
pyruvate fermentation to ethanol I,
2-aminoethylphosphonate degradation I,
ethanol degradation I
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natural substrates
propanal dehydrogenase (CoA-propanoylating)
acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+

Benzoate degradation,
Pyruvate metabolism,
Dioxin degradation,
Xylene degradation,
Metabolic pathways,
Microbial metabolism in diverse environments,
Degradation of aromatic compounds

2-deoxy-D-ribose degradation I,
L-threonine degradation IV,
ethanolamine utilization,
heterolactic fermentation,
triethylamine degradation,
2-deoxy-alpha-D-ribose 1-phosphate degradation,
superpathway of fermentation (Chlamydomonas reinhardtii),
2-hydroxypenta-2,4-dienoate degradation,
pyruvate fermentation to ethanol III,
mixed acid fermentation,
acetylene degradation (anaerobic),
pyruvate fermentation to ethanol I,
2-aminoethylphosphonate degradation I,
ethanol degradation I
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natural substrates
primary-amine oxidase
aminoacetone + H2O + O2 = methylglyoxal + NH3 + H2O2
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natural substrates
monoamine oxidase
aminoacetone + H2O + O2 = methylglyoxal + NH3 + H2O2
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natural substrates
glycine C-acetyltransferase
acetyl-CoA + glycine = CoA + 2-amino-3-oxobutanoate
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natural substrates
aspartate kinase
ATP + L-aspartate = ADP + 4-phospho-L-aspartate

Monobactam biosynthesis,
Cysteine and methionine metabolism,
Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids

3-dehydroquinate biosynthesis II (archaea),
L-methionine biosynthesis IV (archaea),
L-lysine biosynthesis I,
grixazone biosynthesis,
L-lysine biosynthesis VI,
L-lysine biosynthesis III,
L-lysine biosynthesis II,
norspermidine biosynthesis,
spermidine biosynthesis II,
L-homoserine biosynthesis,
ectoine biosynthesis
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natural substrates
aspartate-semialdehyde dehydrogenase
L-aspartate 4-semialdehyde + phosphate + NADP+ = L-4-aspartyl phosphate + NADPH + H+

Cysteine and methionine metabolism,
Lysine biosynthesis,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids

3-dehydroquinate biosynthesis II (archaea),
L-methionine biosynthesis IV (archaea),
L-lysine biosynthesis I,
grixazone biosynthesis,
L-lysine biosynthesis VI,
L-lysine biosynthesis III,
L-lysine biosynthesis II,
norspermidine biosynthesis,
spermidine biosynthesis II,
L-homoserine biosynthesis,
ectoine biosynthesis
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natural substrates
homoserine dehydrogenase
L-homoserine + NADP+ = L-aspartate 4-semialdehyde + NADPH + H+
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natural substrates
phenylserine aldolase
L-threonine = glycine + acetaldehyde
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natural substrates
D-threonine aldolase
L-threonine = glycine + acetaldehyde
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natural substrates
low-specificity L-threonine aldolase
L-threonine = glycine + acetaldehyde
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natural substrates
L-threonine aldolase
L-threonine = glycine + acetaldehyde
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natural substrates
threonine synthase
O-phospho-L-homoserine + H2O = L-threonine + phosphate
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natural substrates
homoserine kinase
ATP + L-homoserine = ADP + O-phospho-L-homoserine
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natural substrates
threonine synthase
L-threonine = 2-oxobutanoate + NH3
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natural substrates, multi-step reaction
L-serine ammonia-lyase
L-threonine = 2-oxobutanoate + NH3
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natural substrates, multi-step reaction
threonine ammonia-lyase
L-threonine = 2-oxobutanoate + NH3
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natural substrates, multi-step reaction
formate C-acetyltransferase
2-oxobutyrate + CoA = propionyl-CoA + formate
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natural substrates
2-oxobutyrate + CoA = propionyl-CoA + formate
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natural substrates
phosphate butyryltransferase
propanoyl-CoA + phosphate = CoA + propanoyl phosphate
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natural substrates
phosphate propanoyltransferase
propanoyl-CoA + phosphate = CoA + propanoyl phosphate
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natural substrates
phosphate acetyltransferase
propanoyl-CoA + phosphate = CoA + propanoyl phosphate
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natural substrates
acetate kinase
ATP + propanoate = ADP + propanoyl phosphate
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natural substrates
branched-chain-fatty-acid kinase
ATP + propanoate = ADP + propanoyl phosphate
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natural substrates
propionate kinase
ATP + propanoate = ADP + propanoyl phosphate
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natural substrates
formate kinase
ATP + propanoate = ADP + propanoyl phosphate
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natural substrates
butyrate kinase
ATP + propanoate = ADP + propanoyl phosphate
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natural substrates
L-threonine 3-dehydrogenase
L-threonine + NAD+ = L-2-amino-3-oxobutanoate + NADH + H+
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natural substrates
diaminobutyrate-pyruvate transaminase
L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate
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natural substrates
diaminobutyrate-2-oxoglutarate transaminase
L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate
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natural substrates
diaminobutyrate decarboxylase
L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate
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natural substrates
threonine-tRNA ligase
ATP + L-threonine + tRNAThr = AMP + diphosphate + L-threonyl-tRNAThr
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natural substrates
pyruvate synthase
2-oxobutyrate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin
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natural substrates, generic, protein
2-oxoacid oxidoreductase (ferredoxin)
2-oxobutyrate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin
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natural substrates, generic, protein
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
2-oxobutyrate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin
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natural substrates, generic, protein
L-threonylcarbamoyladenylate synthase
L-threonine + ATP + HCO3- = L-threonylcarbamoyladenylate + diphosphate + H2O
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natural substrates
N6-L-threonylcarbamoyladenine synthase
L-threonylcarbamoyladenylate + adenine37 in tRNA = AMP + N6-L-threonylcarbamoyladenine37 in tRNA
generic compounds
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natural substrates, nucleotide