Pathways
propionate fermentation (BRENDA)
Print
:= BRENDA, 
:= KEGG, 
:= MetaCyc, 
:= SABIO-RK
:= amino acid sequences 
:= show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
methylmalonyl-CoA = propionyl-CoA + CO2
; "show the reaction diagram")
; "show the reaction diagram")
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: Malonyl-CoA decarboxylase (EryM, Saccharopolyspora erythraea)natural substrates
malonyl-CoA decarboxylase
methylmalonyl-CoA = propionyl-CoA + CO2
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: Malonyl-CoA decarboxylase (EryM, Saccharopolyspora erythraea)natural substrates
ethylmalonyl-CoA decarboxylase
methylmalonyl-CoA = propionyl-CoA + CO2
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: Malonyl-CoA decarboxylase (EryM, Saccharopolyspora erythraea)natural substrates
4.1.1.M5
methylmalonyl-CoA = propionyl-CoA + CO2
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: Malonyl-CoA decarboxylase (EryM, Saccharopolyspora erythraea)natural substrates
carboxymethylproline synthase
methylmalonyl-CoA = propionyl-CoA + CO2
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: Malonyl-CoA decarboxylase (EryM, Saccharopolyspora erythraea)natural substrates
propionyl-CoA carboxylase
methylmalonyl-CoA = propionyl-CoA + CO2
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: Malonyl-CoA decarboxylase (EryM, Saccharopolyspora erythraea)natural substrates
methylmalonyl-CoA epimerase
(R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA
; "show the reaction diagram")
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natural substrates
aconitate hydratase
(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O
; "show the reaction diagram")
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: reversible reaction Ref. 1: Biosci. Biotech. Biochem., 59 (11), 2013-2017, 1995natural substrates
2-methylisocitrate dehydratase
(2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O
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: reversible reaction Ref. 1: Biosci. Biotech. Biochem., 59 (11), 2013-2017, 1995natural substrates
citrate synthase (unknown stereospecificity)
propanoyl-CoA + H2O + oxaloacetate = (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate + CoA
; "show the reaction diagram")
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natural substrates
2-methylcitrate synthase
propanoyl-CoA + H2O + oxaloacetate = (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate + CoA
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natural substrates
isocitrate lyase
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = succinate + pyruvate
; "show the reaction diagram")
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natural substrates
Methylisocitrate lyase
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = succinate + pyruvate
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natural substrates
methylmalonyl-CoA carboxytransferase
(S)-methylmalonyl-CoA + pyruvate = propanoyl-CoA + oxaloacetate
; "show the reaction diagram")
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natural substrates
succinyl-CoA + propionate = propionyl-CoA + succinate
; "show the reaction diagram")
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natural substrates
propionate CoA-transferase
succinyl-CoA + propionate = propionyl-CoA + succinate
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natural substrates
succinyl-CoA:acetate CoA-transferase
succinyl-CoA + propionate = propionyl-CoA + succinate
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natural substrates
2.8.3.M4
succinyl-CoA + propionate = propionyl-CoA + succinate
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natural substrates
methylmalonyl-CoA mutase
(R)-methylmalonyl-CoA = succinyl-CoA
: Valine, leucine and isoleucine degradation,Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,pyruvate fermentation to propanoate I,
methylaspartate cycle,
3-hydroxypropanoate cycle,
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
anaerobic energy metabolism (invertebrates, mitochondrial),
propanoyl CoA degradation I,
conversion of succinate to propanoate
; "show the reaction diagram")
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natural substrates
ethylmalonyl-CoA mutase
(R)-methylmalonyl-CoA = succinyl-CoA
: Valine, leucine and isoleucine degradation,Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,pyruvate fermentation to propanoate I,
methylaspartate cycle,
3-hydroxypropanoate cycle,
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
anaerobic energy metabolism (invertebrates, mitochondrial),
propanoyl CoA degradation I,
conversion of succinate to propanoate
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natural substrates
2-hydroxyisobutanoyl-CoA mutase
(R)-methylmalonyl-CoA = succinyl-CoA
: Valine, leucine and isoleucine degradation,Glyoxylate and dicarboxylate metabolism,
Propanoate metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism
: (S)-lactate fermentation to propanoate, acetate and hydrogen,pyruvate fermentation to propanoate I,
methylaspartate cycle,
3-hydroxypropanoate cycle,
3-hydroxypropanoate/4-hydroxybutanate cycle,
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered),
anaerobic energy metabolism (invertebrates, mitochondrial),
propanoyl CoA degradation I,
conversion of succinate to propanoate
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natural substrates
2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O
; "show the reaction diagram")
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natural substrates
2-methylcitrate dehydratase
(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O
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natural substrates