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BRENDA KEGG MetaCyc

proline metabolism (BRENDA)

:= BRENDA, := KEGG, := MetaCyc, := SABIO-RK
:= amino acid sequences := show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
proline dehydrogenase
L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor
BR51015 show the reaction diagram
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natural substrates, generic
proline dehydrogenase (acceptor)
L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor
BR51015 show the reaction diagram
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natural substrates, generic
D-proline reductase
D-proline + NADH = 5-aminopentanoic acid + NAD+
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natural substrates
succinate-semialdehyde dehydrogenase (NAD+)
L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + H+
BR36889 show the reaction diagram
R00245 show the reaction diagram
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: the second step of two-step reaction (see R00707, R03314+R00245) following after R03314
natural substrates
glutamate-5-semialdehyde dehydrogenase
L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + H+
BR36889 show the reaction diagram
R00245 show the reaction diagram
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: the second step of two-step reaction (see R00707, R03314+R00245) following after R03314
natural substrates
aldehyde dehydrogenase [NAD(P)+]
L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + H+
BR36889 show the reaction diagram
R00245 show the reaction diagram
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: the second step of two-step reaction (see R00707, R03314+R00245) following after R03314
natural substrates
L-glutamate gamma-semialdehyde dehydrogenase
L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + H+
BR36889 show the reaction diagram
R00245 show the reaction diagram
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: the second step of two-step reaction (see R00707, R03314+R00245) following after R03314
natural substrates
2,5-diaminovalerate transaminase
2,5-diaminopentanoate + 2-oxoglutarate = 5-amino-2-oxopentanoate + L-glutamate
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natural substrates
SPONTANEOUS
5-Amino-2-oxopentanoic acid <=> 1-Pyrroline-2-carboxylate + H2O
BR52882 show the reaction diagram
R03249 show the reaction diagram
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: non-enzymatic
natural substrates
0.0.0.0
spontaneous reaction
5-Amino-2-oxopentanoic acid <=> 1-Pyrroline-2-carboxylate + H2O
BR52882 show the reaction diagram
R03249 show the reaction diagram
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: non-enzymatic
natural substrates
1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]
L-proline + NADP+ = 1-pyrroline-2-carboxylate + NADPH + H+
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: NAD+ (see R01246)
natural substrates
1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
L-proline + NADP+ = 1-pyrroline-2-carboxylate + NADPH + H+
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: NAD+ (see R01246)
natural substrates
thiomorpholine-carboxylate dehydrogenase
L-proline + NADP+ = 1-pyrroline-2-carboxylate + NADPH + H+
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: NAD+ (see R01246)
natural substrates
1-pyrroline-2-carboxylate reductase [NAD(P)H]
L-proline + NADP+ = 1-pyrroline-2-carboxylate + NADPH + H+
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: NAD+ (see R01246)
natural substrates
L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2
R10507 show the reaction diagram
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natural substrates
proline dehydrogenase
L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2
R10507 show the reaction diagram
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natural substrates
proline dehydrogenase (acceptor)
L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2
R10507 show the reaction diagram
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natural substrates
4-hydroxyproline epimerase
L-proline = D-proline
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natural substrates
D-proline dehydrogenase
D-proline + acceptor = 1-pyrroline-2-carboxylate + reduced acceptor
BR49168 show the reaction diagram
R09496 show the reaction diagram
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natural substrates, generic
proline-tRNA ligase
ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
BR45 show the reaction diagram
R03661 show the reaction diagram
404
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natural substrates
glutamate-tRNA ligase
ATP + L-proline + tRNAPro = AMP + diphosphate + L-prolyl-tRNAPro
BR45 show the reaction diagram
R03661 show the reaction diagram
404
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natural substrates