glycine reductase
Pathways
glycine metabolism (BRENDA)






EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
acetyl phosphate + NH3 + thioredoxin disulfide + H2O = glycine + phosphate + thioredoxin
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natural substrates, generic
acetate kinase
ATP + acetate = ADP + acetyl phosphate

Pyruvate metabolism,
Methane metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism

L-lysine fermentation to acetate and butanoate,
purine nucleobases degradation I (anaerobic),
(S)-lactate fermentation to propanoate, acetate and hydrogen,
acetate and ATP formation from acetyl-CoA I,
glycine degradation (reductive Stickland reaction),
ethanolamine utilization,
methanogenesis from acetate,
Bifidobacterium shunt,
purine nucleobases degradation II (anaerobic),
superpathway of fermentation (Chlamydomonas reinhardtii),
mixed acid fermentation,
pyruvate fermentation to acetate IV,
acetylene degradation (anaerobic),
pyruvate fermentation to acetate II
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natural substrates
propionate kinase
ATP + acetate = ADP + acetyl phosphate

Pyruvate metabolism,
Methane metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism

L-lysine fermentation to acetate and butanoate,
purine nucleobases degradation I (anaerobic),
(S)-lactate fermentation to propanoate, acetate and hydrogen,
acetate and ATP formation from acetyl-CoA I,
glycine degradation (reductive Stickland reaction),
ethanolamine utilization,
methanogenesis from acetate,
Bifidobacterium shunt,
purine nucleobases degradation II (anaerobic),
superpathway of fermentation (Chlamydomonas reinhardtii),
mixed acid fermentation,
pyruvate fermentation to acetate IV,
acetylene degradation (anaerobic),
pyruvate fermentation to acetate II
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natural substrates
carbamate kinase
ATP + acetate = ADP + acetyl phosphate

Pyruvate metabolism,
Methane metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism

L-lysine fermentation to acetate and butanoate,
purine nucleobases degradation I (anaerobic),
(S)-lactate fermentation to propanoate, acetate and hydrogen,
acetate and ATP formation from acetyl-CoA I,
glycine degradation (reductive Stickland reaction),
ethanolamine utilization,
methanogenesis from acetate,
Bifidobacterium shunt,
purine nucleobases degradation II (anaerobic),
superpathway of fermentation (Chlamydomonas reinhardtii),
mixed acid fermentation,
pyruvate fermentation to acetate IV,
acetylene degradation (anaerobic),
pyruvate fermentation to acetate II
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natural substrates
phosphoribosylglycinamide formyltransferase
ATP + acetate = ADP + acetyl phosphate

Pyruvate metabolism,
Methane metabolism,
Carbon fixation pathways in prokaryotes,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism

L-lysine fermentation to acetate and butanoate,
purine nucleobases degradation I (anaerobic),
(S)-lactate fermentation to propanoate, acetate and hydrogen,
acetate and ATP formation from acetyl-CoA I,
glycine degradation (reductive Stickland reaction),
ethanolamine utilization,
methanogenesis from acetate,
Bifidobacterium shunt,
purine nucleobases degradation II (anaerobic),
superpathway of fermentation (Chlamydomonas reinhardtii),
mixed acid fermentation,
pyruvate fermentation to acetate IV,
acetylene degradation (anaerobic),
pyruvate fermentation to acetate II
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natural substrates
glycine oxidase
glycine + H2O + O2 = glyoxylate + NH3 + H2O2
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natural substrates
L-amino-acid oxidase
glycine + H2O + O2 = glyoxylate + NH3 + H2O2
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natural substrates
D-amino-acid oxidase
glycine + H2O + O2 = glyoxylate + NH3 + H2O2
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natural substrates
glycine dehydrogenase (cytochrome)
glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c + 2 H+
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natural substrates, protein
glutamine-pyruvate transaminase
L-alanine + glyoxylate = pyruvate + glycine
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natural substrates
beta-alanine-pyruvate transaminase
L-alanine + glyoxylate = pyruvate + glycine
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natural substrates
alanine transaminase
L-alanine + glyoxylate = pyruvate + glycine
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natural substrates
glycine transaminase
L-alanine + glyoxylate = pyruvate + glycine
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natural substrates
(R)-3-amino-2-methylpropionate-pyruvate transaminase
L-alanine + glyoxylate = pyruvate + glycine
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natural substrates
alanine-glyoxylate transaminase
L-alanine + glyoxylate = pyruvate + glycine
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natural substrates
serine-glyoxylate transaminase
L-alanine + glyoxylate = pyruvate + glycine
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natural substrates
serine-pyruvate transaminase
L-alanine + glyoxylate = pyruvate + glycine
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natural substrates
kynurenine-oxoglutarate transaminase
L-alanine + glyoxylate = pyruvate + glycine
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natural substrates
amine transaminase
L-alanine + glyoxylate = pyruvate + glycine
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natural substrates
glutamine-pyruvate transaminase
L-serine + glyoxylate = 3-hydroxypyruvate + glycine

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natural substrates
glycine-oxaloacetate transaminase
L-serine + glyoxylate = 3-hydroxypyruvate + glycine

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natural substrates
glycine transaminase
L-serine + glyoxylate = 3-hydroxypyruvate + glycine

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natural substrates
alanine-glyoxylate transaminase
L-serine + glyoxylate = 3-hydroxypyruvate + glycine

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natural substrates
serine-glyoxylate transaminase
L-serine + glyoxylate = 3-hydroxypyruvate + glycine

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natural substrates
serine-pyruvate transaminase
L-serine + glyoxylate = 3-hydroxypyruvate + glycine

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natural substrates
aromatic-amino-acid-glyoxylate transaminase
L-serine + glyoxylate = 3-hydroxypyruvate + glycine

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natural substrates
glycine hydroxymethyltransferase
5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine

Cyanoamino acid metabolism,
Glyoxylate and dicarboxylate metabolism,
One carbon pool by folate,
Methane metabolism,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
Biosynthesis of amino acids

formaldehyde assimilation I (serine pathway),
photorespiration,
folate transformations III (E. coli),
folate polyglutamylation,
glycine betaine degradation II (mammalian),
folate transformations II (plants),
purine nucleobases degradation II (anaerobic),
glycine biosynthesis I,
glycine betaine degradation I
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natural substrates
alanine transaminase
glycine + 2-oxoglutarate = glyoxylate + L-glutamate
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natural substrates
glycine transaminase
glycine + 2-oxoglutarate = glyoxylate + L-glutamate
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natural substrates
branched-chain-amino-acid transaminase
glycine + 2-oxoglutarate = glyoxylate + L-glutamate
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natural substrates
alanine-glyoxylate transaminase
glycine + 2-oxoglutarate = glyoxylate + L-glutamate
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natural substrates
5-aminovalerate transaminase
glycine + 2-oxoglutarate = glyoxylate + L-glutamate
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natural substrates
aromatic-amino-acid-glyoxylate transaminase
glycine + 2-oxoglutarate = glyoxylate + L-glutamate
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natural substrates
kynurenine-oxoglutarate transaminase
glycine + 2-oxoglutarate = glyoxylate + L-glutamate
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natural substrates
glycine amidinotransferase
L-arginine + glycine = L-ornithine + guanidinoacetate
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natural substrates
guanidinoacetate N-methyltransferase
S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine
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natural substrates
alcohol oxidase
glycolate + O2 = glyoxylate + H2O2
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natural substrates
(S)-2-hydroxy-acid oxidase
glycolate + O2 = glyoxylate + H2O2
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natural substrates