Print
asparaginyl-tRNA synthase (glutamine-hydrolysing)
Pathways
glutamate and glutamine metabolism (BRENDA)
:= BRENDA, 
:= KEGG, 
:= MetaCyc, 
:= SABIO-RK
:= amino acid sequences 
:= show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
ATP + L-glutamyl-tRNAGln + L-glutamine = ADP + phosphate + L-glutaminyl-tRNAGln + L-glutamate
; "show the reaction diagram")
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natural substrates
glutaminyl-tRNA synthase (glutamine-hydrolysing)
ATP + L-glutamyl-tRNAGln + L-glutamine = ADP + phosphate + L-glutaminyl-tRNAGln + L-glutamate
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natural substrates
succinate-semialdehyde dehydrogenase [NAD(P)+]
succinate semialdehyde + NADP+ + H2O = succinate + NADPH + H+
; "show the reaction diagram")
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: NADH (see R00713)natural substrates
succinate-semialdehyde dehydrogenase (NAD+)
succinate semialdehyde + NADP+ + H2O = succinate + NADPH + H+
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: NADH (see R00713)natural substrates
2,5-dioxovalerate dehydrogenase
succinate semialdehyde + NADP+ + H2O = succinate + NADPH + H+
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: NADH (see R00713)natural substrates
succinate-semialdehyde dehydrogenase (NADP+)
succinate semialdehyde + NADP+ + H2O = succinate + NADPH + H+
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: NADH (see R00713)natural substrates
aldose reductase
succinate semialdehyde + NADP+ + H2O = succinate + NADPH + H+
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: NADH (see R00713)natural substrates
6-aminohexanoate aminotransferase
4-aminobutanoate + pyruvate = succinate semialdehyde + L-alanine
; "show the reaction diagram")
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natural substrates
beta-alanine-pyruvate transaminase
4-aminobutanoate + pyruvate = succinate semialdehyde + L-alanine
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natural substrates
4-aminobutyrate-2-oxoglutarate transaminase
4-aminobutanoate + pyruvate = succinate semialdehyde + L-alanine
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natural substrates
(R)-3-amino-2-methylpropionate-pyruvate transaminase
4-aminobutanoate + pyruvate = succinate semialdehyde + L-alanine
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natural substrates
4-aminobutyrate-pyruvate transaminase
4-aminobutanoate + pyruvate = succinate semialdehyde + L-alanine
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natural substrates
isocitrate lyase
(2S)-2-hydroxy-2-methylbutanedioate = acetate + pyruvate
; "show the reaction diagram")
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: multi-step reaction (see R03153+R00237)natural substrates, multi-step reaction
citramalate lyase
(2S)-2-hydroxy-2-methylbutanedioate = acetate + pyruvate
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: multi-step reaction (see R03153+R00237)natural substrates, multi-step reaction
fumarate hydratase
(S)-2-Methylmalate = 2-methylfumarate + H2O
; "show the reaction diagram")
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natural substrates
(S)-2-methylmalate dehydratase
(S)-2-Methylmalate = 2-methylfumarate + H2O
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natural substrates
methylaspartate ammonia-lyase
L-threo-3-methylaspartate = mesaconate + NH3
; "show the reaction diagram")
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natural substrates
methylaspartate mutase
L-threo-3-methylaspartate = L-glutamate
; "show the reaction diagram")
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natural substrates
propionate CoA-transferase
butyryl-CoA + acetate = acetyl-CoA + butanoate
; "show the reaction diagram")
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natural substrates
5-hydroxypentanoate CoA-transferase
butyryl-CoA + acetate = acetyl-CoA + butanoate
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natural substrates
acetate CoA-transferase
butyryl-CoA + acetate = acetyl-CoA + butanoate
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natural substrates
butyrate-acetoacetate CoA-transferase
butyryl-CoA + acetate = acetyl-CoA + butanoate
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natural substrates
acyl-CoA dehydrogenase (NADP+)
crotonyl-CoA + reduced acceptor = butyryl-CoA + oxidized acceptor
generic compounds
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natural substrates, generic
short-chain acyl-CoA dehydrogenase
crotonyl-CoA + reduced acceptor = butyryl-CoA + oxidized acceptor
generic compounds
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natural substrates, generic
7.2.4.5
glutaconyl-CoA decarboxylase
(2E)-4-carboxybut-2-enoyl-CoA + Na+[side 1] = (2E)-but-2-enoyl-CoA + CO2 + Na+[side 2]
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natural substrates
(R)-2-hydroxyglutaryl-CoA = (E)-glutaconyl-CoA + H2O
; "show the reaction diagram")
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natural substrates
(R)-2-hydroxyglutaryl-CoA dehydratase
(R)-2-hydroxyglutaryl-CoA = (E)-glutaconyl-CoA + H2O
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natural substrates
aspartate ammonia-lyase
L-aspartate = fumarate + NH3
; "show the reaction diagram")
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natural substrates
methylaspartate ammonia-lyase
L-aspartate = fumarate + NH3
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natural substrates
2-oxoglutaramate amidase
2-oxoglutaramate + H2O = 2-oxoglutarate + NH3
; "show the reaction diagram")
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natural substrates
omega-amidase
2-oxoglutaramate + H2O = 2-oxoglutarate + NH3
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natural substrates
N-methyl-2-oxoglutaramate hydrolase
2-oxoglutaramate + H2O = 2-oxoglutarate + NH3
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natural substrates
glutamine-pyruvate transaminase
L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine
; "show the reaction diagram")
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natural substrates
serine-pyruvate transaminase
L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine
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natural substrates
amino-acid racemase
L-glutamate = D-glutamate
; "show the reaction diagram")
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natural substrates
glutamate racemase
L-glutamate = D-glutamate
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natural substrates
arginine racemase
L-glutamate = D-glutamate
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natural substrates
asparaginase
L-glutamine + H2O = L-glutamate + NH3
; "show the reaction diagram")
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
glutaminase
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
glutamin-(asparagin-)ase
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
peptidyl-glutaminase
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
protein-glutamine glutaminase
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
imidazole glycerol phosphate synthase
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
imidazole glycerol-phosphate synthase
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
pyridoxal 5'-phosphate synthase (glutamine hydrolysing)
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
CTP synthase (glutamine hydrolysing)
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
lipid II isoglutaminyl synthase (glutamine-hydrolysing)
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
GMP synthase (glutamine-hydrolysing)
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
asparagine synthase (glutamine-hydrolysing)
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
carbamoyl-phosphate synthase (glutamine-hydrolysing)
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
asparaginyl-tRNA synthase (glutamine-hydrolysing)
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
glutaminyl-tRNA synthase (glutamine-hydrolysing)
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
tryptophanyl aminopeptidase
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
gamma-glutamyltransferase
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
amidophosphoribosyltransferase
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
glutamate synthase (NADPH)
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
glutamate synthase (NADH)
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
glutamate synthase (ferredoxin)
L-glutamine + H2O = L-glutamate + NH3
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: the first step of several ligases (ec 6.3.5.x) using glutamine as amide-N-donor ec 6.3.5.4 (see R00578, R00256+R00483) ec 6.3.5.5 (see R00575, R00256+R10948+R10949+R01395)natural substrates
glutamine synthetase
ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine
; "show the reaction diagram")
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natural substrates
glutamate synthase (ferredoxin)
2 L-glutamate + oxidized ferredoxin = L-glutamine + 2-oxoglutarate + reduced ferredoxin + 2 H+
; "show the reaction diagram")
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: two-step reaction (see R00256+R10086)natural substrates, generic, protein
glutamate synthase (NADH)
2 L-glutamate + NAD+ = L-glutamine + 2-oxoglutarate + NADH + H+
; "show the reaction diagram")
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natural substrates
glutamate synthase (NADPH)
2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+
; "show the reaction diagram")
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: two-step reaction (see R00256+R00248)natural substrates
glutamate synthase (NAD(P)H)
2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+
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: two-step reaction (see R00256+R00248)natural substrates
glutamate synthase (NADPH)
L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+
; "show the reaction diagram")
: 757-
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: NADH (ec 1.4.1.3, see R00243)natural substrates
glutamate dehydrogenase
L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+
: 757-
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: NADH (ec 1.4.1.3, see R00243)natural substrates
glutamate dehydrogenase [NAD(P)+]
L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+
: 757-
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: NADH (ec 1.4.1.3, see R00243)natural substrates
glutamate dehydrogenase (NADP+)
L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+
: 757-
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: NADH (ec 1.4.1.3, see R00243)natural substrates
L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+
: 757-
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: NADH (ec 1.4.1.3, see R00243)natural substrates
glutamate synthase (NADH)
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Taurine and hypotaurine metabolism,
D-Glutamine and D-glutamate metabolism,
Nitrogen metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
: L-ornithine biosynthesis II,GABA shunt,
L-glutamate biosynthesis II,
L-glutamate degradation X,
L-glutamate degradation V (via hydroxyglutarate),
methylaspartate cycle,
4-aminobutanoate degradation V,
ethylene biosynthesis IV (engineered),
L-alanine degradation II (to D-lactate),
L-glutamate degradation I
; "show the reaction diagram")
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: NADPH (ec 1.4.1.3 and 1.4.1.4, see R00248)natural substrates
glutamate dehydrogenase
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Taurine and hypotaurine metabolism,
D-Glutamine and D-glutamate metabolism,
Nitrogen metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
: L-ornithine biosynthesis II,GABA shunt,
L-glutamate biosynthesis II,
L-glutamate degradation X,
L-glutamate degradation V (via hydroxyglutarate),
methylaspartate cycle,
4-aminobutanoate degradation V,
ethylene biosynthesis IV (engineered),
L-alanine degradation II (to D-lactate),
L-glutamate degradation I
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: NADPH (ec 1.4.1.3 and 1.4.1.4, see R00248)natural substrates
glutamate dehydrogenase [NAD(P)+]
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Taurine and hypotaurine metabolism,
D-Glutamine and D-glutamate metabolism,
Nitrogen metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
: L-ornithine biosynthesis II,GABA shunt,
L-glutamate biosynthesis II,
L-glutamate degradation X,
L-glutamate degradation V (via hydroxyglutarate),
methylaspartate cycle,
4-aminobutanoate degradation V,
ethylene biosynthesis IV (engineered),
L-alanine degradation II (to D-lactate),
L-glutamate degradation I
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: NADPH (ec 1.4.1.3 and 1.4.1.4, see R00248)natural substrates
glutamate dehydrogenase (NADP+)
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Taurine and hypotaurine metabolism,
D-Glutamine and D-glutamate metabolism,
Nitrogen metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
: L-ornithine biosynthesis II,GABA shunt,
L-glutamate biosynthesis II,
L-glutamate degradation X,
L-glutamate degradation V (via hydroxyglutarate),
methylaspartate cycle,
4-aminobutanoate degradation V,
ethylene biosynthesis IV (engineered),
L-alanine degradation II (to D-lactate),
L-glutamate degradation I
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: NADPH (ec 1.4.1.3 and 1.4.1.4, see R00248)natural substrates
L-amino-acid dehydrogenase
L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Taurine and hypotaurine metabolism,
D-Glutamine and D-glutamate metabolism,
Nitrogen metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments
: L-ornithine biosynthesis II,GABA shunt,
L-glutamate biosynthesis II,
L-glutamate degradation X,
L-glutamate degradation V (via hydroxyglutarate),
methylaspartate cycle,
4-aminobutanoate degradation V,
ethylene biosynthesis IV (engineered),
L-alanine degradation II (to D-lactate),
L-glutamate degradation I
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: NADPH (ec 1.4.1.3 and 1.4.1.4, see R00248)natural substrates
aspartate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
; "show the reaction diagram")
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natural substrates
4-aminobutyrate-2-oxoglutarate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
alanine transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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-
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natural substrates
2-aminoadipate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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-
-
-
natural substrates
branched-chain-amino-acid transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
-
-
-
-
natural substrates
tyrosine transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
-
-
-
-
natural substrates
aromatic-amino-acid transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
cysteine-conjugate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
aspartate-prephenate aminotransferase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
glutamate-prephenate aminotransferase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
glutamate decarboxylase
L-glutamate = 4-aminobutanoate + CO2
; "show the reaction diagram")
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natural substrates
tyrosine decarboxylase
L-glutamate = 4-aminobutanoate + CO2
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natural substrates
sulfinoalanine decarboxylase
L-glutamate = 4-aminobutanoate + CO2
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natural substrates
4-aminobutyrate-2-oxoglutarate transaminase
4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate
; "show the reaction diagram")
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natural substrates
alanine transaminase
4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate
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natural substrates
(S)-3-amino-2-methylpropionate transaminase
4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate
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natural substrates
diamine transaminase
4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate
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natural substrates
5-aminovalerate transaminase
4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate
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natural substrates
4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+
; "show the reaction diagram")
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natural substrates
glucuronate reductase
4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+
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natural substrates
alcohol dehydrogenase (NADP+)
4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+
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natural substrates
glyoxylate reductase
4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+
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natural substrates
4-hydroxybutyrate dehydrogenase
4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+
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natural substrates
glyoxylate reductase (NADP+)
4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+
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natural substrates
succinate semialdehyde reductase (NADPH)
4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+
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natural substrates
1.1.1.co
4-hydroxybutanoate + NADP+ = succinate semialdehyde + NADPH + H+
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natural substrates
succinate-semialdehyde dehydrogenase [NAD(P)+]
succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+
; "show the reaction diagram")
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: NADP+ (ec 1.2.1.16, see R00714)natural substrates
aminobutyraldehyde dehydrogenase
succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+
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: NADP+ (ec 1.2.1.16, see R00714)natural substrates
glycolaldehyde dehydrogenase
succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+
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: NADP+ (ec 1.2.1.16, see R00714)natural substrates
succinate-semialdehyde dehydrogenase (NAD+)
succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+
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: NADP+ (ec 1.2.1.16, see R00714)natural substrates
2,5-dioxovalerate dehydrogenase
succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+
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: NADP+ (ec 1.2.1.16, see R00714)natural substrates
aldehyde dehydrogenase (NAD+)
succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+
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: NADP+ (ec 1.2.1.16, see R00714)natural substrates
succinate-semialdehyde dehydrogenase (NADP+)
succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+
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: NADP+ (ec 1.2.1.16, see R00714)natural substrates
L-glutamate gamma-semialdehyde dehydrogenase
succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+
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: NADP+ (ec 1.2.1.16, see R00714)natural substrates
2-oxoglutarate reductase
(R)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+
; "show the reaction diagram")
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natural substrates
phosphoglycerate dehydrogenase
(R)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+
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natural substrates
L-2-hydroxyglutarate dehydrogenase
(R)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+
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natural substrates
glutaconate CoA-transferase
acetyl-CoA + (R)-2-hydroxyglutarate = acetate + (R)-2-hydroxyglutaryl-1-CoA
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natural substrates
glutamate-tRNA ligase
ATP + L-glutamate + tRNAGlx = AMP + diphosphate + glutamyl-tRNAGlx
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natural substrates, nucleotide
glutamine-tRNA ligase
ATP + L-glutamate + tRNAGlx = AMP + diphosphate + glutamyl-tRNAGlx
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natural substrates, nucleotide
glutamate-tRNAGln ligase
ATP + L-glutamate + tRNAGlx = AMP + diphosphate + glutamyl-tRNAGlx
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natural substrates, nucleotide
lysine-tRNA ligase
ATP + L-glutamate + tRNAGlx = AMP + diphosphate + glutamyl-tRNAGlx
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natural substrates, nucleotide
glutamyl-Q-tRNA(Asp) ligase
ATP + L-glutamate + tRNAGlx = AMP + diphosphate + glutamyl-tRNAGlx
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natural substrates, nucleotide