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Pathways

degradation of sugar alcohols (BRENDA)

:= BRENDA,

:= KEGG,

:= MetaCyc,

:= SABIO-RK

:= amino acid sequences

:= show the reaction diagram

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EC Number

Reaction

Pathways

Reaction IDs

Stoichiometry Check

Missing Substrate

Missing Product

Commentary

Remark

2.7.1.121

phosphoenolpyruvate-glycerone phosphotransferase

phosphoenolpyruvate + glycerone = pyruvate + glycerone phosphate

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V

: BR47735

: R01012

: 2.7.1.121-RXN

: 1304

natural substrates

1.1.1.-

glycerol + NAD+ = glycerone + NADH + H+

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V,
glycerol degradation II,
cytidine-5'-diphosphate-glycerol biosynthesis

: BR47364

: R01034

: GLYCDEH-RXN

, RXN-11708_WOP

: 1322

natural substrates

1.1.1.1

alcohol dehydrogenase

glycerol + NAD+ = glycerone + NADH + H+

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V,
glycerol degradation II,
cytidine-5'-diphosphate-glycerol biosynthesis

: BR47364

: R01034

: GLYCDEH-RXN

, RXN-11708_WOP

: 1322

natural substrates

1.1.1.11

D-arabinitol 4-dehydrogenase

glycerol + NAD+ = glycerone + NADH + H+

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V,
glycerol degradation II,
cytidine-5'-diphosphate-glycerol biosynthesis

: BR47364

: R01034

: GLYCDEH-RXN

, RXN-11708_WOP

: 1322

natural substrates

1.1.1.14

L-iditol 2-dehydrogenase

glycerol + NAD+ = glycerone + NADH + H+

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V,
glycerol degradation II,
cytidine-5'-diphosphate-glycerol biosynthesis

: BR47364

: R01034

: GLYCDEH-RXN

, RXN-11708_WOP

: 1322

natural substrates

1.1.1.156

glycerol 2-dehydrogenase (NADP+)

glycerol + NAD+ = glycerone + NADH + H+

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V,
glycerol degradation II,
cytidine-5'-diphosphate-glycerol biosynthesis

: BR47364

: R01034

: GLYCDEH-RXN

, RXN-11708_WOP

: 1322

natural substrates

1.1.1.202

1,3-propanediol dehydrogenase

glycerol + NAD+ = glycerone + NADH + H+

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V,
glycerol degradation II,
cytidine-5'-diphosphate-glycerol biosynthesis

: BR47364

: R01034

: GLYCDEH-RXN

, RXN-11708_WOP

: 1322

natural substrates

1.1.1.21

aldose reductase

glycerol + NAD+ = glycerone + NADH + H+

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V,
glycerol degradation II,
cytidine-5'-diphosphate-glycerol biosynthesis

: BR47364

: R01034

: GLYCDEH-RXN

, RXN-11708_WOP

: 1322

natural substrates

1.1.1.287

D-arabinitol dehydrogenase (NADP+)

glycerol + NAD+ = glycerone + NADH + H+

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V,
glycerol degradation II,
cytidine-5'-diphosphate-glycerol biosynthesis

: BR47364

: R01034

: GLYCDEH-RXN

, RXN-11708_WOP

: 1322

natural substrates

1.1.1.6

glycerol dehydrogenase

glycerol + NAD+ = glycerone + NADH + H+

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V,
glycerol degradation II,
cytidine-5'-diphosphate-glycerol biosynthesis

: BR47364

: R01034

: GLYCDEH-RXN

, RXN-11708_WOP

: 1322

natural substrates

1.1.1.9

D-xylulose reductase

glycerol + NAD+ = glycerone + NADH + H+

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V,
glycerol degradation II,
cytidine-5'-diphosphate-glycerol biosynthesis

: BR47364

: R01034

: GLYCDEH-RXN

, RXN-11708_WOP

: 1322

natural substrates

1.1.99.22

glycerol dehydrogenase (acceptor)

glycerol + NAD+ = glycerone + NADH + H+

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation V,
glycerol degradation II,
cytidine-5'-diphosphate-glycerol biosynthesis

: BR47364

: R01034

: GLYCDEH-RXN

, RXN-11708_WOP

: 1322

natural substrates

2.7.1.28

triokinase

ATP + glycerone = ADP + glycerone phosphate

: degradation of sugar alcohols

: Glycerolipid metabolism,
Methane metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism

: formaldehyde assimilation III (dihydroxyacetone cycle),
glycerol degradation II

: BR47768

: R01011

: GLYCERONE-KINASE-RXN

: 1303

natural substrates

2.7.1.29

glycerone kinase

ATP + glycerone = ADP + glycerone phosphate

: degradation of sugar alcohols

: Glycerolipid metabolism,
Methane metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism

: formaldehyde assimilation III (dihydroxyacetone cycle),
glycerol degradation II

: BR47768

: R01011

: GLYCERONE-KINASE-RXN

: 1303

natural substrates

2.7.1.30

glycerol kinase

ATP + glycerone = ADP + glycerone phosphate

: degradation of sugar alcohols

: Glycerolipid metabolism,
Methane metabolism,
Metabolic pathways,
Microbial metabolism in diverse environments,
Carbon metabolism

: formaldehyde assimilation III (dihydroxyacetone cycle),
glycerol degradation II

: BR47768

: R01011

: GLYCERONE-KINASE-RXN

: 1303

natural substrates

3.1.1.5

lysophospholipase

2-acylglycerophosphocholine + H2O = fatty acid + glycerylphosphocholine

: degradation of sugar alcohols

: BS73293

generic

1.1.1.12

L-arabinitol 4-dehydrogenase

D-sorbitol + NAD+ = D-fructose + NADH + H+

: degradation of sugar alcohols

: Fructose and mannose metabolism,
Metabolic pathways

: BS165118

, BS187172

: R00875

: 1206, 8396

natural substrates

1.1.1.14

L-iditol 2-dehydrogenase

D-sorbitol + NAD+ = D-fructose + NADH + H+

: degradation of sugar alcohols

: Fructose and mannose metabolism,
Metabolic pathways

: BS165118

, BS187172

: R00875

: 1206, 8396

natural substrates

1.1.1.15

D-iditol 2-dehydrogenase

D-sorbitol + NAD+ = D-fructose + NADH + H+

: degradation of sugar alcohols

: Fructose and mannose metabolism,
Metabolic pathways

: BS165118

, BS187172

: R00875

: 1206, 8396

natural substrates

1.1.1.16

galactitol 2-dehydrogenase

D-sorbitol + NAD+ = D-fructose + NADH + H+

: degradation of sugar alcohols

: Fructose and mannose metabolism,
Metabolic pathways

: BS165118

, BS187172

: R00875

: 1206, 8396

natural substrates

1.1.1.21

aldose reductase

D-sorbitol + NAD+ = D-fructose + NADH + H+

: degradation of sugar alcohols

: Fructose and mannose metabolism,
Metabolic pathways

: BS165118

, BS187172

: R00875

: 1206, 8396

natural substrates

1.1.1.9

D-xylulose reductase

D-sorbitol + NAD+ = D-fructose + NADH + H+

: degradation of sugar alcohols

: Fructose and mannose metabolism,
Metabolic pathways

: BS165118

, BS187172

: R00875

: 1206, 8396

natural substrates

1.1.99.21

D-sorbitol dehydrogenase (acceptor)

D-sorbitol + NAD+ = D-fructose + NADH + H+

: degradation of sugar alcohols

: Fructose and mannose metabolism,
Metabolic pathways

: BS165118

, BS187172

: R00875

: 1206, 8396

natural substrates

1.1.1.251

galactitol-1-phosphate 5-dehydrogenase

galactitol 1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+

: degradation of sugar alcohols

: Galactose metabolism,
Metabolic pathways

: BR920

: R05571

natural substrates

2.7.1.11

6-phosphofructokinase

ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

: degradation of sugar alcohols,
metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: galactitol degradation,
lactose and galactose degradation I,
N-acetyl-D-galactosamine degradation,
D-galactosamine and N-acetyl-D-galactosamine degradation

: BR47754

: R03236

: TAGAKIN-RXN

: 3059

natural substrates

2.7.1.144

tagatose-6-phosphate kinase

ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

: degradation of sugar alcohols,
metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: galactitol degradation,
lactose and galactose degradation I,
N-acetyl-D-galactosamine degradation,
D-galactosamine and N-acetyl-D-galactosamine degradation

: BR47754

: R03236

: TAGAKIN-RXN

: 3059

natural substrates

2.7.1.56

1-phosphofructokinase

ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

: degradation of sugar alcohols,
metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: galactitol degradation,
lactose and galactose degradation I,
N-acetyl-D-galactosamine degradation,
D-galactosamine and N-acetyl-D-galactosamine degradation

: BR47754

: R03236

: TAGAKIN-RXN

: 3059

natural substrates

4.1.2.13

fructose-bisphosphate aldolase

D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate

: degradation of sugar alcohols,
metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: D-tagatose degradation,
galactitol degradation,
lactose and galactose degradation I,
N-acetyl-D-galactosamine degradation,
D-galactosamine and N-acetyl-D-galactosamine degradation

: BR372

: R01069

: TAGAALDOL-RXN

: 1339

natural substrates

4.1.2.40

tagatose-bisphosphate aldolase

D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate

: degradation of sugar alcohols,
metabolism of disaccharids

: Galactose metabolism,
Metabolic pathways

: D-tagatose degradation,
galactitol degradation,
lactose and galactose degradation I,
N-acetyl-D-galactosamine degradation,
D-galactosamine and N-acetyl-D-galactosamine degradation

: BR372

: R01069

: TAGAALDOL-RXN

: 1339

natural substrates

1.1.1.17

mannitol-1-phosphate 5-dehydrogenase

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+

: degradation of sugar alcohols

: Fructose and mannose metabolism,
Metabolic pathways

: mannitol cycle,
mannitol degradation I

: BR36702

: R00758

, R02703

: MANNPDEHYDROG-RXN

: 1115

natural substrates

2.7.1.16

ribulokinase

ATP + D-xylulose = ADP + D-xylulose 5-phosphate

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: D-arabinitol degradation I,
D-xylose degradation I,
xylitol degradation I

: BR48062

: R01639

: XYLULOKIN-RXN

: 1779

natural substrates

2.7.1.17

xylulokinase

ATP + D-xylulose = ADP + D-xylulose 5-phosphate

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: D-arabinitol degradation I,
D-xylose degradation I,
xylitol degradation I

: BR48062

: R01639

: XYLULOKIN-RXN

: 1779

natural substrates

1.1.1.10

L-xylulose reductase

D-arabinitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: D-arabinitol degradation I

: BR29175

: R05604

: D-ARABINITOL-4-DEHYDROGENASE-RXN

natural substrates

1.1.1.11

D-arabinitol 4-dehydrogenase

D-arabinitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: D-arabinitol degradation I

: BR29175

: R05604

: D-ARABINITOL-4-DEHYDROGENASE-RXN

natural substrates

1.1.1.14

L-iditol 2-dehydrogenase

D-arabinitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: D-arabinitol degradation I

: BR29175

: R05604

: D-ARABINITOL-4-DEHYDROGENASE-RXN

natural substrates

1.1.1.287

D-arabinitol dehydrogenase (NADP+)

D-arabinitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: D-arabinitol degradation I

: BR29175

: R05604

: D-ARABINITOL-4-DEHYDROGENASE-RXN

natural substrates

1.1.1.56

ribitol 2-dehydrogenase

D-arabinitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: D-arabinitol degradation I

: BR29175

: R05604

: D-ARABINITOL-4-DEHYDROGENASE-RXN

natural substrates

1.1.1.67

mannitol 2-dehydrogenase

D-arabinitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: D-arabinitol degradation I

: BR29175

: R05604

: D-ARABINITOL-4-DEHYDROGENASE-RXN

natural substrates

1.1.5.3

glycerol-3-phosphate dehydrogenase

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol

: degradation of sugar alcohols

: BR48992

, BS401894

: R00849

natural substrates

2.7.1.30

glycerol kinase

ATP + glycerol = ADP + sn-glycerol 3-phosphate

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation I

: BR47770

: R00847

: GLYCEROL-KIN-RXN

: 99

natural substrates

2.7.2.1

acetate kinase

ATP + glycerol = ADP + sn-glycerol 3-phosphate

: degradation of sugar alcohols

: Glycerolipid metabolism,
Metabolic pathways

: glycerol degradation I

: BR47770

: R00847

: GLYCEROL-KIN-RXN

: 99

natural substrates

1.1.1.114

apiose 1-reductase

ribitol + NAD+ = D-ribulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: ribitol degradation I

: BR29319

: R01895

: RIBITOL-2-DEHYDROGENASE-RXN

: 1953

natural substrates

1.1.1.14

L-iditol 2-dehydrogenase

ribitol + NAD+ = D-ribulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: ribitol degradation I

: BR29319

: R01895

: RIBITOL-2-DEHYDROGENASE-RXN

: 1953

natural substrates

1.1.1.287

D-arabinitol dehydrogenase (NADP+)

ribitol + NAD+ = D-ribulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: ribitol degradation I

: BR29319

: R01895

: RIBITOL-2-DEHYDROGENASE-RXN

: 1953

natural substrates

1.1.1.56

ribitol 2-dehydrogenase

ribitol + NAD+ = D-ribulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: ribitol degradation I

: BR29319

: R01895

: RIBITOL-2-DEHYDROGENASE-RXN

: 1953

natural substrates

1.1.1.9

D-xylulose reductase

ribitol + NAD+ = D-ribulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: ribitol degradation I

: BR29319

: R01895

: RIBITOL-2-DEHYDROGENASE-RXN

: 1953

natural substrates

1.1.1.10

L-xylulose reductase

xylitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: xylitol degradation I

: BR26053

, BR49523

: R01896

, R05831

: D-XYLULOSE-REDUCTASE-RXN

, RXN-11825

: 1954, 8244

natural substrates

1.1.1.14

L-iditol 2-dehydrogenase

xylitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: xylitol degradation I

: BR26053

, BR49523

: R01896

, R05831

: D-XYLULOSE-REDUCTASE-RXN

, RXN-11825

: 1954, 8244

natural substrates

1.1.1.15

D-iditol 2-dehydrogenase

xylitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: xylitol degradation I

: BR26053

, BR49523

: R01896

, R05831

: D-XYLULOSE-REDUCTASE-RXN

, RXN-11825

: 1954, 8244

natural substrates

1.1.1.250

D-arabinitol 2-dehydrogenase

xylitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: xylitol degradation I

: BR26053

, BR49523

: R01896

, R05831

: D-XYLULOSE-REDUCTASE-RXN

, RXN-11825

: 1954, 8244

natural substrates

1.1.1.9

D-xylulose reductase

xylitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: xylitol degradation I

: BR26053

, BR49523

: R01896

, R05831

: D-XYLULOSE-REDUCTASE-RXN

, RXN-11825

: 1954, 8244

natural substrates

1.1.1.B19

xylitol dehydrogenase (NAD+)

xylitol + NAD+ = D-xylulose + NADH + H+

: degradation of sugar alcohols

: Pentose and glucuronate interconversions,
Metabolic pathways

: xylitol degradation I

: BR26053

, BR49523

: R01896

, R05831

: D-XYLULOSE-REDUCTASE-RXN

, RXN-11825

: 1954, 8244

natural substrates

1.1.1.140

sorbitol-6-phosphate 2-dehydrogenase

D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+

: degradation of sugar alcohols

: BR29206

: R07133

natural substrates