Pathways
aspartate and asparagine metabolism (BRENDA)
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:= BRENDA, 
:= KEGG, 
:= MetaCyc, 
:= SABIO-RK
:= amino acid sequences 
:= show the reaction diagram
EC Number
Reaction
Pathways
Reaction IDs
Stoichiometry Check
Missing Substrate
Missing Product
Commentary
Remark
2-oxosuccinamate + H2O = 2-oxosuccinate + NH3
; "show the reaction diagram")
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natural substrates
omega-amidase
2-oxosuccinamate + H2O = 2-oxosuccinate + NH3
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natural substrates
tryptophanyl aminopeptidase
L-asparagine + H2O = L-aspartate + NH3
; "show the reaction diagram")
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natural substrates
beta-aspartyl-peptidase
L-asparagine + H2O = L-aspartate + NH3
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natural substrates
asparaginase
L-asparagine + H2O = L-aspartate + NH3
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natural substrates
aryl-acylamidase
L-asparagine + H2O = L-aspartate + NH3
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natural substrates
glutaminase
L-asparagine + H2O = L-aspartate + NH3
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natural substrates
N4-(beta-N-acetylglucosaminyl)-L-asparaginase
L-asparagine + H2O = L-aspartate + NH3
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natural substrates
omega-amidase
L-asparagine + H2O = L-aspartate + NH3
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natural substrates
glutamin-(asparagin-)ase
L-asparagine + H2O = L-aspartate + NH3
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natural substrates
cyanoalanine nitrilase
L-asparagine + H2O = L-aspartate + NH3
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natural substrates
asparagine synthase (glutamine-hydrolysing)
ATP + L-aspartate + L-glutamine + H2O = AMP + diphosphate + L-asparagine + L-glutamate
; "show the reaction diagram")
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: two-step reaction (see R00256+R00483)natural substrates
aspartate-ammonia ligase
ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine
; "show the reaction diagram")
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: second step of multi-step reaction (ec 6.3.5.4, see R00578, R00256+R00483)natural substrates, multi-step reaction
asparagine synthase (glutamine-hydrolysing)
ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine
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: second step of multi-step reaction (ec 6.3.5.4, see R00578, R00256+R00483)natural substrates, multi-step reaction
aspartate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
; "show the reaction diagram")
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natural substrates
4-aminobutyrate-2-oxoglutarate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
alanine transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
2-aminoadipate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
branched-chain-amino-acid transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
tyrosine transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
aromatic-amino-acid transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
cysteine-conjugate transaminase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
aspartate-prephenate aminotransferase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
glutamate-prephenate aminotransferase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
: Arginine biosynthesis,Alanine, aspartate and glutamate metabolism,
Carbon fixation in photosynthetic organisms,
Metabolic pathways,
Biosynthesis of secondary metabolites,
Microbial metabolism in diverse environments,
Carbon metabolism,
2-Oxocarboxylic acid metabolism,
Biosynthesis of amino acids
: C4 photosynthetic carbon assimilation cycle, PEPCK type,C4 photosynthetic carbon assimilation cycle, NAD-ME type,
L-aspartate degradation I,
L-asparagine degradation III (mammalian),
anaerobic energy metabolism (invertebrates, cytosol),
partial TCA cycle (obligate autotrophs),
L-aspartate biosynthesis,
L-glutamate degradation II,
malate/L-aspartate shuttle pathway
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natural substrates
aspartate-tRNA ligase
ATP + L-aspartate + tRNAAsx = AMP + diphosphate + L-aspartyl-tRNAAsx
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natural substrates, nucleotide
aspartate-tRNAAsn ligase
ATP + L-aspartate + tRNAAsx = AMP + diphosphate + L-aspartyl-tRNAAsx
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natural substrates, nucleotide
aspartate-tRNA ligase
ATP + L-asparagine + tRNAAsn = AMP + diphosphate + L-asparaginyl-tRNAAsn
; "show the reaction diagram")
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natural substrates, nucleotide
asparagine-tRNA ligase
ATP + L-asparagine + tRNAAsn = AMP + diphosphate + L-asparaginyl-tRNAAsn
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natural substrates, nucleotide